Pregled bibliografske jedinice broj: 51652
Protection of flupirtine on beta-amyloid-induced apoptosis in neuronal cells in vitro - prevention of amyloid-induced glutathione depletion
Protection of flupirtine on beta-amyloid-induced apoptosis in neuronal cells in vitro - prevention of amyloid-induced glutathione depletion // Journal of Neurochemistry, 68 (1997), 6; 2371-2377 (međunarodna recenzija, članak, znanstveni)
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Naslov
Protection of flupirtine on beta-amyloid-induced apoptosis in neuronal cells in vitro - prevention of amyloid-induced glutathione depletion
Autori
Muller, W.E.G. ; Romero, F.J. ; Perović, Sanja ; Pergande, G. ; Pialoglou, P.
Izvornik
Journal of Neurochemistry (0022-3042) 68
(1997), 6;
2371-2377
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Alzheimers disease; amyloid; amyotrophic lateral sclerosis; oxidative stress; flupirtine; triaminopyridine
Sažetak
Effective drugs are not available to protect against beta-amyloid peptide (A beta)-induced neurotoxicity. COrtical neurons from rat embryos were treated with the toxic fragment A beta 25-35 at 1 mu M in the presence or absence of flupirtine, a triaminopyridine, successfully applied clinically as nonopiate analgesic drug.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
