Naslov
PERFORMANCE OF THE STATSTRIP GLUCOSE HOSPITAL METER IN PATIENTS WITH DIABETIC NEPHROPATHY

Autori
Božičević, Sandra ; Radišić Biljak, Vanja ; Pavković, Pajica ; Milić, Violeta ; Vučić Lovrenčić, Marijana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Clinical Chemisty and Laboratory Medicine / - Berlin : New York : Walter de Gruyter, 2011, S671-S671

Skup
IFCC WorldLab Euromedlab Berlin 2011

Mjesto i datum
Berlin, Njemačka, 15.05.2011. - 19.05.2011

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
glucose; diabetic nephropathy; hematocrit interference

Sažetak
Background. Interference of hemoconcentration/hemodilution in point-of care glucose testing is well described and correction algorithms used to overcome this problem have limited effects. StatStrip Hospital Glucose Meter provides unique correction for hematocrit, which is simultaneously measured with glucose on the same strip. Methods. The performance of the point-of-care StatStrip Glucose Hospital Meter was assessed in patients with various stages of diabetic nephropathy, associated with anemia (decreased hematocrit levels). Results were compared to the reference hexokinase procedure on Olympus AU400 analyzer. Results. Total of 74 diabetic patients with confirmed diabetic nephropathy were included in this evaluation [age-range=23–83, median= 62, 5 years ; male/female= 52/22, HbA1c range=4, 5 to 10, 4, median=6, 8%]. Hematocrit levels ranged from 0, 236 – 0, 489 L/L, with 54, 1% results below lower limit of reference intervals, and plasma glucose range was 2, 0-17, 6 mmol/L. Median glucose values were 9, 2 and 9, 0 mmol/L for hexokinase and StatStrip, respectively, with 0, 2 mmol/L absolute bias, which is in accordance with desirable specifications for bias derived from intra- and inter-individual biologic variation (2, 2%). Agreement with the hexokinase method was excellent: y = 0.9318x + 0.06705 (Passing Bablok regression) with no significant deviation from linearity (P>0, 10). In a subgroup of patients with low hematocrit Passing-Bablok regression also showed excellent agreement with the hexokinase method (y = 0.9355x – 0, 01613) with no significant deviation from linearity (P>0, 10). Conclusions. StatStrip Glucose Meter can be used as an accurate and reliable tool for monitoring glucose levels in patients with diabetic nephropathy associated with anemia.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA