Naslov
Pokazatelji oksidacijskog oštećenja makromolekula i antioksidacijske obrane u ispitanika izloženih radarskom zračenju frekvencija od 1, 5 GHz - 10, 9 GHz
(Indicators of macromolecular oxidative damage and antioxidant defence in examinees exposed to the radar frequencies 1.5-10.9 GHz)

Autori
Marjanović, Ana Marija ; Domijan, Ana-Marija ; Flajs, Dubravka ; Pavičić, Ivan

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
Zbornik radova osmog simpozija hrvatskog društva za zaštitu od zračenja = Proceedings of the eight Symposium of the Croatian Radiation Protection Association / Krajcar Bronić, Ines ; Kopjar, N. ; Milić, M. ; Branica, G. - Zagreb : Hrvatsko društvo za zaštitu od zračenja, 2011, 513-519

ISBN
9789539613363

Skup
Simpozij hrvatskog društva za zaštitu od zračenja (8 ; 2011)

Mjesto i datum
Krk, Hrvatska, 13.04.2011. - 15.04.2011

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
mikrovalno zračenje ; protein-karbonil ; glutation ; malondialdehid
(microwave radiation ; protein carbonyls ; glutathione malondialdeyde)

Sažetak
Radar is an object-detection system which uses microwaves (Mw). As a result of increased use of radar there is a rising concern regarding health effects of Mw radiation on human body. Living organisms are complex electrochemical systems being evolved in a relatively narrow range of well-defined environmental parameters. For life to be maintained these parameters must be kept within their normal range ; since deviations can induce biochemical effects causing cell function impairment and disease. Some theories indicate connection between Mw radiation, oxidative damage as well as antioxidant defence of organism. Aim of this study was to evaluate level and damage of macromolecular structures ; proteins and lipids in blood of men occupationally exposed to Mw radiation. Concentration of glutathione (GSH) a known indicator of organism antioxidant defence was also determined. Blood samples were collected from 27 male workers occupationally exposed to radar frequencies 1.5-10.9 GHz. Corresponding control group (N=8) was a part of study. Concentrations of total and oxidised proteins, protein carbonyls, and GSH were measured by spectrophotometric method, while malondialdeyde (MDA), product of lipid peroxidation, was determined by high performance liquid chromatography (HPLC). Gained concentrations of oxidised proteins, GSH and MDA were presented in relation to total proteins. Concentration of oxidised proteins between control and exposed group of examinees didn’t show any significant statistical difference. However, concentration of GSH in exposed group was found considerably decreased, while concentration of MDA was found to be increased. Results indicate that Mw radiation of radar operating at frequencies 1.5-10.9 GHz could cause damage to proteins and lipids in addition to impairment of antioxidant defence of organism.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Temeljne medicinske znanosti

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