Naslov
Genetic research in psychiatric patients - some bioethical aspects

Autori
Folnegović-Šmalc, Vera ; Uzun, Suzana ; Mimica, Ninoslav

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Proceedings of 40th International Neuropsychiatric Pula Symposium. U: Neurologia Croatia 49 (Suppl.2) / Barac, Boško ; Huber, Gerd ; Lechner, Helmut ; Muačević, Vasko - Zagreb : Denona, 2000, 23-24

Skup
40th International Neuropsychiatric Pula Symposium

Mjesto i datum
Pula, Hrvatska, 21.06.2000. - 24.06.2000

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
genetic research ; psychiatric patients ; bioethical aspects

Sažetak
Psychiatric patients are especially vulnerable population and cannot always fully participate in informed – consent processes due to specific psychiatric symptoms. In our recent psychiatric practice, a written informed consent is obtained only in clinical psychopharmacological and genetic research as well as in cases of psychiatric involuntary hospitalisations. The participate of informed consent is a cornerstone of medical practice, but one that has been widely ignored in the context of medical investigations, particulary if these are not in themselves dangerous, even though their consequences may be profound. Statments with signatures for investigators and patients that the study was fully explained to the patient have been present in all informed consents. Genetic testing falls into this category. A useful definition of genetic testing might be that „Genetic testing is analysis of specific gene, its product or function, or other DNA and chromosome analysis, to detect or exclude an alteration likely to be associated with genetic disorder.“ The first Croatian Law on protection of persons with mental disorders, which came into power on January, 1 st 1998, defines informed consent as a consent given in free will by a person with a mental disorder for undergoing a certain medical procedure, which is based upon an adequate knowledge about the purpose, nature, consequences, benefits and dangers of such a procedure and about alternative possibilities of treatment. The same Law defines medical procedure as a specific form of treatment, diagnostic procedure, admittance and hospitalization in psychiatric institution for diagnostic purpose and treatment, including in educational programs which take place in psychiatric institutions, and research in the field of protection and improvement of health of the persons with mental disorders. Many patients in psychiatry are incapable of consenting legally. Such „vulnerable“ persons receive special protection by specific laws, rules and regulations (ICH- GCP, Croatian Law on Drugs and medical Products, Law on Protection of Persons with Mental Disorders). The participants are always informed on the confidentiality of genetic results, as well as on the right to refuse to enter the trial or to withdraw from the trial, stressing that the participation in the research is totally voluntary. It is of great necessity to provide adequate education for all experts included in this process.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

Napomena
Indexed/Abstracted in: Neuroscience Citation Index ;
EMBASE/Excerpta Medica ; Bowker Int. Series Data
Base

POVEZANOST RADA