Pregled bibliografske jedinice broj: 505009
Expression of bacteriophage derived scFv and their incorporation into third generation porphyrin immunoconjugates for targeted PDT
Expression of bacteriophage derived scFv and their incorporation into third generation porphyrin immunoconjugates for targeted PDT // Postgraduate Research Conference 2005: The Theory, Therapies and Technologies of Clinical Biosciences
Kingston upon Hull, Ujedinjeno Kraljevstvo, 2005. (predavanje, nije recenziran, neobjavljeni rad, znanstveni)
CROSBI ID: 505009 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Expression of bacteriophage derived scFv and their incorporation into third generation porphyrin immunoconjugates for targeted PDT
Autori
Staneloudi, Chrysovalanto ; Smith, Karen A. ; Hudson, Robert ; Peša, Nela ; Savoie, Huguette ; Boyle, Ross W. ; Greenman, John
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni
Skup
Postgraduate Research Conference 2005: The Theory, Therapies and Technologies of Clinical Biosciences
Mjesto i datum
Kingston upon Hull, Ujedinjeno Kraljevstvo, 17.06.2005
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Nije recenziran
Ključne riječi
Porphyrin; Photodynamic therapy; Bioconjugation; scFv; Phage display
Sažetak
An expression system giving high yield of scFv fragments has been established. The molar ratios at which the conjugation to scFv was carried out has been optimized. These immunoconjugates showed low levels of non-covalently associated porhyrin, minimizing potential non-specific cytotoxicity.
Izvorni jezik
Engleski
Znanstvena područja
Kemija, Biologija, Kliničke medicinske znanosti
