Pregled bibliografske jedinice broj: 504717
Characterisation of novel porphyrin-antibody conjugates for use in photodynamic therapy of cancer
Characterisation of novel porphyrin-antibody conjugates for use in photodynamic therapy of cancer // International Journal of Molecular Medicine / Spandidos, Demetrios A. (ur.).
Atena: Spandidos Publications, 2003. str. S64-S64 (poster, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 504717 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Characterisation of novel porphyrin-antibody conjugates for use in photodynamic therapy of cancer
Autori
Smith, Karen A. ; Madden, Leigh A. ; Hudson, Robert ; Pesa, Nela ; Swann, Joanne ; Savoie, Huguette ; Boyle, Ross W. ; Greenman, John
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
International Journal of Molecular Medicine
/ Spandidos, Demetrios A. - Atena : Spandidos Publications, 2003, S64-S64
Skup
8th World Congress on Advances in Oncology and 6th International Symposium on Molecular Medicine
Mjesto i datum
Kreta, Grčka, 16.10.2003. - 18.10.2003
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
Bioconjugation; Porphyrin; Monoclonal antibody; Photodynamic therapy; Cancer
Sažetak
The synthesis of several three cationic 5, 15-diphenyl porphyrins, bearing an isothiocyanate group for conjugation to proteins is described. The potential of these compounds as targeted photosensitisers for use in photodynamic therapy (PDT) is demonstrated by their efficient conjugation to monoclonal antibodies and the ability of the bioconjugates to bind cancer cells that express the corresponding antigen.
Izvorni jezik
Engleski
Znanstvena područja
Kemija, Biologija, Temeljne medicinske znanosti
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
