Naslov
Side effects of antidementives

Autori
Mimica, Ninoslav ; Presečki, Paola

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
1. hrvatski kongres o nuspojavama psihofarmaka s međunarodnim sudjelovanjem - Zbornik sažetaka / Jakovljević, Miro ; Uzun, Suzana ; Kozumplik, Oliver - Zagreb : Hrvatsko društvo za kliničku psihijatriju HLZ-a ; Hrvatsko društvo za biologijsku psihijatriju i psihofarmakoterapiju HLZ-a, 2009, 28-28

Skup
1. hrvatski kongres o nuspojavama psihofarmaka s međunarodnim sudjelovanjem

Mjesto i datum
Osijek, Hrvatska, 26.02.2009. - 01.03.2009

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Domaća recenzija

Ključne riječi
antidementives; side effects

Sažetak
The aim of this lecture is to describe side effects of five antidementives which are approved by the United State Food and Drug Administration (FDA) ; four acetylcholinesterase inhibitors and one glutamate – or N-metil-D-aspartat receptor antagonist – memantine. In general antidementives are well tolerated and undesired effects are rare ; except hepatotoxicity of tacrine and gastrointestinal side effects of donepezil, rivastigmine, galantamine and tacrine that result form acetylcholinesterase inhibition. Nausea, diarrhea, vomiting, and weight loss are the most common side effects of the acetylcholinesterase inhibitors. Patient tend to become tolerant to the adverse events rapidly. Significant cholinergic side effects can occur in patients receiving higher doses and often they are related to the rate of initial titration of medication. Medications should be restarted at lowest doses after temporarily stopping. Memantine is the first noncholinesterase inhibitor indicated for Alzheimer’s disease. The side effects which may occur during the treatment with memantine are constipation, dizziness, headache and confusion. These effects, if appears, are mild end transient. Memantine is generally well tolerated.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA