Pregled bibliografske jedinice broj: 501131
A rational approach to screen for hydrated forms of the pharmaceutical derivative magnesium naproxen using liquid-assisted grinding
A rational approach to screen for hydrated forms of the pharmaceutical derivative magnesium naproxen using liquid-assisted grinding // Crystengcomm, 13 (2011), 9; 2125-2129 doi:10.1039/C0CE00894J (međunarodna recenzija, članak, znanstveni)
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Naslov
A rational approach to screen for hydrated forms of the pharmaceutical derivative magnesium naproxen using liquid-assisted grinding
Autori
Friščić, Tomislav ; Halasz, Ivan ; Strobridge, Fiona C. ; Dinnebier, Robert E. ; Stein, Robin S. ; Laszlo, Fabian ; Curfs, Caroline
Izvornik
Crystengcomm (1466-8033) 13
(2011), 9;
2125-2129
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
liquid-assisted grinding; pharmaceutical; screening; naproxen; hydrate
Sažetak
Variation of water content in liquid-assisted grinding was utilised to mechanochemically screen for different hydrated forms of magnesium naproxen directly from a mixture of magnesium oxide and naproxen. Structure determination from powder and single crystal X-ray diffraction data, supported by solid-state NMR and synchrotron radiation diffraction experiments, revealed a monohydrate coordination polymer, a discrete tetrahydrate complex, and provided a preliminary structural model for a highly hydrated salt.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
