Naslov
Should primary PCI be performed and should it be performed fast

Autori
Babić, Zdravko ; Nikolić Heitzler, Vjeran ; Bulj Nikola ; Mavrić, Željko ; Tomulić, Vjekoslav.

Izvornik
Liječnički vijesnik (0024-3477) 128 (2006); 103-103

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo

Ključne riječi
Myocardial infarction; Primary PCI

Sažetak
Introduction : Reocclusion of affected conorary artery is cornerstone of the modern therapy of acute myocardial infarction with ST-elevation ( STEMI). Authors prospectively compared major adverse cardiovascular events (MACE) in one year follow up in the patients sufered STEMI and treated with one of reperfusion strategies: thrombolysis or primary PCI. Materials and methods: 147 patients who suffered STEMI were treated with primary PCI or thrombolysis in two Croatian clinics: University Hospital Sestre milosrdnice, Zagreb and University Hospital Center , Rijeka. After one year follow up frequency of MACE ( angina pectoris- AP, re-PCI, coronary artery by-pass graft-CABG, reinfarction, stroke and death ) was calculated and compared according to patients characteristics and reperfusion strategy used. Results: Higher mortality rate and frequency of MACE in general were found in older patients (p<0.01) and female sex (p<0.05). Older patients had also higher rate of AP and stroke (p<0.05). Patients treated with thrombolysis had higher rate of AP and MACE in general comparing with those treated with primary PCI (p<0.01). In patients treated with primary PCI the shorter was pain-to-door time (p< 0.05) and pain-to-ballon time (p<0.01) the lower was frequency of AP and MACE in general. In all investigated patients the shorter was pain-to-treatment time, the lower was frequency of MACE in general (p<0.05). Discussion and conclussion :This results confirm the superiority of primary PCI in the therapy of STEMI, as well as importance of short time between pain onset and reperfusion. Higher age and female sex are negative predictive factors in patients with STEMI.

Izvorni jezik
Engleski

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