Naslov
Severity and prognosis of acute coronary syndromes in patients with metabolic syndromes.

Autori
Babić, Zdravko ; Nikolić-Heitzler, Vjeran ; Bulj, Nikola ; Pavlov, Marin ; Radeljić, Vjekoslav ; Krčmar, Tomislav ; Erdeljić, Viktorija.

Izvornik
European journal of cardiovascular prevention & rehabilitation (1741-8267) 13 (2006); S23-S23

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo

Ključne riječi
Metabolic syndrome; Acute coronary syndrome

Sažetak
Metabolic syndrome is a combination of visceral obesity, arterial hypertension, insulin resistance, glucose intolerance and dyslipidaemia. This entity causes increased cardiovascular risk in 25-35% of developed world population and it can be expected that prevalence of this syndrome will increase in quoted growing old population. It can be expected that acute coronary syndromes are more severe and have worse prognosis in patients with criteria for metabolic syndrome. In this study the authors collected data on 267 patients who had suffered from acute coronary syndromes (STEMI, NSTEMI, unstable angina pectoris) and were hospitalized in the Coronary Care Unit, University Hospital “Sestre milosrdnice”, Zagreb, Croatia. Investigated patients were divided in three groups: group with metabolic syndrome, group of obese patients without criteria for metabolic syndrome and lean patients group. The groups of patients were compared according to the severity level and the prognosis of acute coronary syndromes. The severity of the acute coronary syndromes was estimated using the cardioselective markers value, ECG changes, echocardiography and coronarography findings, early and late complications, the number of days of hospitalization in CCU, and also the general and cardiovascular in-hospital mortality. Prognosis of the acute coronary syndromes was estimated by incidence of MACE during follow up period of 1 year including general mortality, the appearance and CCS level of angina pectoris and rehospitalization rate. In conclusion, authors found the significant difference among the investigated groups. The highest level of severity and the worst prognosis of acute coronary syndromes were in patients with metabolic syndrome what emphasizes importance of diagnosis and treatment of that syndrome.

Izvorni jezik
Engleski

POVEZANOST RADA