Naslov
Focal Porokeratosis of Nuchae: Case Report

Autori
Štulhofer Buzina, Daška ; Rajič Svjetlana ; Radoš, Jaka ; Marinović, Branka ; Lipozenčić Jasna

Izvornik
Acta dermatovenerologica Croatica (1330-027X) 18 (2010), 4; 257-260

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, prikaz, stručni

Ključne riječi
porokeratosis ; psoriasis ; misdiagnosis

Sažetak
Porokeratosis is the common name of several diseases of unknown patogenesis, which are similar in clinical appearance. It was first described in 1893 and was thought to be a disorder of sweat glands, hence the name porokeratosis. The lesion that can be found in all cases is annular, with atrophic centre, and hyperkeratotic outer ring. Cases of porokeratosis have been linked with genetic heritage, excessive ultraviolet exposure, kidney failure, and state of immunosupression, but no definitive link has been established. As a rare condition, its main feature is that the correct diagnosis can be delayed for a significant period of time. Porokeratotic lesions have high incidence for malignant transformation and are considered premalignant. In this paper, we present a case where a porokeratotic lesion has been unsuccessfully treated as a psoriatic lesion for more than a year in a patient with previously diagnosed psoriasis. A skin biopsy was performed at our department, which revealed classic cornoid lamella and, thus, established the correct diagnosis. The lesion was excised. Additional diagnostic tests revealed normal kidney function and intact immune system. A follow-up protocol has been established for the patient, ensuring timely diagnosis of any future porokeratotic lesions. Porokeratosis, especially when there are only few lesions, is not difficult to manage – once it is diagnosed. Diagnosis of porokeratosis may also aid in identifying a serious systemic disease, such as kidney failure. Importantly, a misdiagnosis of porokeratosis may lead to development of skin cancer.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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