Naslov
Abrogation of antiproliferative effects of cholestatic serum on human lymphocytes by peptidoglycan-monomer linked with zinc (PGM-Zn)

Autori
Ravlić-Gulan, Jagoda ; Radošević-Stašić, Biserka ; Štimac, Davor ; Rukavina, Daniel

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Programme / Hrvatsko imunološko društvo - Zagreb : Hrvatsko imunološko društvo, 1999

Skup
Annual meeting of the Croatian Immunological Society

Mjesto i datum
Zagreb, Hrvatska, 25.11.1999

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
PGM-Zn; jaundice; immunodysfunction

Sažetak
Since in our previous experiments we observed that peptidoglycan-monomer linked with zinc (PGM-Zn) has immuno and hepato-corrective abilities, in this study we tested its effects in vivo in mice subjected to common bile duct ligation (CBDL) and in vitro on blastic transformation of human peripheral blood mononuclear cells (PBMNC). Obstructive jaundice provoked by CBDL induced in mice. The data showed that jaundice induced changes at the level of thymus, liver and spleen, as well as, abrogating properties of icteric serum on blastic trasformation of lymphocytes might partially corrected by PGM-Zn similarly .

Izvorni jezik
Engleski

POVEZANOST RADA