Naslov
Screening of ionic liquids for the synthesis of isoamyl acetate by immobilized Candida antarctica lipase B

Autori
Cvjetko, Marina ; Vorkapić-Furač, Jasna ; Žnidaršič Plazl, Polona

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
ESBES & ISPPP & ISB Symposia 2010 / - , 2010

Skup
ESBES & ISPPP & ISB Symposia 2010

Mjesto i datum
Bologna, Italija, 06.09.2010. - 08.09.2010

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Ionic liquids; Isoamyl acetate; Novozym 435

Sažetak
The use of ionic liquids as possible replacement for conventional molecular solvents for catalytic and organic reactions has been the subject of considerable recent attention because of their prospects for “green” catalysis. Features that make ionic liquids attractive for use in organic synthesis in general and catalytic processes in particular include their lack of vapor pressure, great dissolving power, no flammabillity, as well as high thermal, chemical and electrochemical stability. Since the number of combinations of anions and cations encompassed by ionic liquids is vast, the physical and chemical properties of ionic liquids (hydrophobicity, density, viscosity, melting point, polarity, etc.) may be tunable by changing/modificating the anion and/or the cation to design an optimal IL for each specific enzymatic reaction system. This important feature of ILs allows to improve enzyme solubility, to increase substrate/product solubility, to modify enzyme selectivity, to enhance enzyme stability, or to tailor the reaction rate. In this study, nine different ionic liquids (ILs) based on quaternary imidazolium cations, with alkyl, alkenyl, alkynil, benzyl and N-aminopropyl side chains, associated with bis[(trifluoromethane)sulfonyl]imide and hexafluorophosphate anion, were synthesized and their suitability, together with several commercial imidazolium, pyridinium and pyrolidinium based ionic liquids, for immobilized Candida antartica lipase B-catalysed synthesis of isoamyl acetate in a continuously operated microreactor was assayed.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija

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