Naslov
Synthesis of ionic liquids and their use as solvents for biocatalysis in microreactors

Autori
Cvjetko, Marina ; Vorkapić-Furač, Jasna ; Pohar, Andrej ; Žnidaršič Plazl, Polona

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
Implementation of microreactor technology into biotechnology / - Ljubljana, 2010

Skup
Implementation of microreactor technology into biotechnology

Mjesto i datum
Ljubljana, Slovenija, 29.09.2010. - 30.09.2010

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Nije recenziran

Ključne riječi
Esterification; Ionic liquids; Isoamyl acetate; Lipase; Microreactor

Sažetak
The use of ionic liquid as reaction media for immobilized Candida antartica lipase B catalyzed synthesis of isoamyl acetate was investigated. For this purpose, a wide range of di- and trisubstituted imidazolium-based ILs containing bis[(trifluoromethane)sulfonyl]imide and hexafluorophosphate anion were prepared. Water-immiscible ILs containing [Tf2N] anion appeared to be suitable media for the proposed reaction, with values of enzyme activity and conversion comparable to classical organic solvent, n-heptane. The highest activity and overall yield was achieved in 1-heptyl-2, 3-methylimidazolium bis[(trifluoromethyl)sulfonyl]imide, [hpdmim][Tf2N]. This IL was used to study continuous flow synthesis of isoamyl acetate in miniaturized reactor packed with immobilized Candida antarctica lipase B.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija

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