Naslov
Mycological contamination of stored herbal drugs

Autori
Cvetnić, Zdenka ; Pepeljnjak, Stjepan

Izvornik
Acta Pharmaceutica (1330-0075) 49 (1999), 3; 201-209

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
mycological contamination; drug plants; aflatoxin B1

Sažetak
The fungal flora of 85 samples of dried herbal drugs belonging to 53 species was determined. The moulds of the genera Aspergillus (62.3 %), Rhizopus (42.3 %) and Penicillium (41.1 %) were most frequently observed. Aflatoxigenicity and ochratoxigenicity detection of Aspergillus flavus and A. ochraceus strains were assayed by specific fluorescence test under long wavelengh UV-light (365 nm) in aflatoxin-producing ability medium (APA). Only one out of fifteen A. flavus strains investigated showed fluorescence and was found to be aflatoxin B1 producer. The strain was isolated from stored sample of Gentiana radix. The concentration of toxin obtained from fluorescent APA medium was 0.75 g g-1. Of three A. ochraceus strains neither produced ochratoxin A or aflatoxin B1. It is suggested that plant material intented for medical use should be stored under suitable conditions to prevent growth of naturally occurring toxigenic fungi.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

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