Pregled bibliografske jedinice broj: 494283
Electrophysiological Effects, Efficacy And Safety Of Intravenous Propafenone In Termination Of Atrioventricular Nodal Reentrant Tachycardia (Avnrt) And Atrioventricular Reentrant Tachycardia (Avrt): Prospective Non-Randomized Interventional Study.
Electrophysiological Effects, Efficacy And Safety Of Intravenous Propafenone In Termination Of Atrioventricular Nodal Reentrant Tachycardia (Avnrt) And Atrioventricular Reentrant Tachycardia (Avrt): Prospective Non-Randomized Interventional Study. // Acta clinica Croatica, 49 (2010), 1; 73-76 (međunarodna recenzija, članak, znanstveni)
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Naslov
Electrophysiological Effects, Efficacy And Safety
Of Intravenous Propafenone In Termination Of
Atrioventricular Nodal Reentrant Tachycardia
(Avnrt) And Atrioventricular Reentrant Tachycardia
(Avrt): Prospective Non-Randomized Interventional
Study.
Autori
H. Pintarić, Manola Šime, J. Szavits-Nossan, N. Pavlović, D. Delić-Brkljačić, V. Radeljić
Izvornik
Acta clinica Croatica (0353-9466) 49
(2010), 1;
73-76
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
AVNRT ; AVRT ; propafenon
Sažetak
The aim of this prospective, non-randomized interventional study was to assess electrophysiological effects, efficacy and safety of intravenous propafenone in termination of atrioventricular nodal reentrant tachycardia (AVNRT) and orthodromic atrioventricular reentrant tachycardia (AVRT). This single-center study was carried out at Department of Cardiology, Sestre milosrdnice University Hospital in Zagreb, Croatia, between January 1, 2005 and December 31, 2006. Eligibility requirements were fulfilled by a total of 70 patients with AVNRT (n=37) and AVRT (n=33). The intervention consisted of the electrophysiological study aimed at inducing tachycardia, followed by intravenous administration of 2 mg/kg propafenone in both groups. The main outcome measures were safety and efficacy of 2 mg/kg intravenous propafenone in tachycardia termination and re-induction. Out of 37 patients with AVNRT, propafenone managed to terminate it in 28 (75.7%) patients, while tachycardia was not inducible in 25 (67.56%) patients. Out of 33 patients with AVRT, propafenone managed to terminate AVRT in 29 (87.9%) patients, while tachycardia was not inducible in 22 (66.66%) patients. The overall propafenone efficacy in tachycardia termination was 81.42%. No propafenone-related adverse effects were recorded during the study period. Propafenone was found to be a safe and effective anti- arrhythmic drug and can be justifiably administered for AVNRT and AVRT termination. It could be considered as an alternative to adenosine and verapamil.
Izvorni jezik
Engleski
POVEZANOST RADA
Ustanove:
Medicinski fakultet, Zagreb,
KBC "Sestre Milosrdnice"
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- SCI-EXP, SSCI i/ili A&HCI
