Naslov
MULTILAYER VERSUS MONOLAYER AMNIOTIC MEMBRANE TRANSPLANTATION IN DEEP CORNEAL ULCER TREATMENT FOR DEEP CORNEAL ULCER TREATMENT

Autori
Dekaris, Iva ; Gabrić, Nikica ; Mravičić, Ivana ; Karaman, Željka ; Kaštelan, Snježana ; Špoljarić, Ninoslav

Izvornik
Collegium Antropologicum (0350-6134) 25 (Suppl) (2001); 23-28

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
multilayer AMT; monolayer AMT; corneal ulcer

Sažetak
Purpose: To evaluate the efficacy of multilayer amniotic transplantation (AMT) for reconstruction of corneal stroma and epithelium. Patients and methods: Corneal ulcer (n=28) resulted as a consequence of previous infectious or neurotrophic keratitis. In the first group (n=17) ulcer was covered with monolayer AM, while in the other group (n=11) two or more layers of AM were situated into the ulcer and then whole cornea was covered with AM sheet. Results: Monolayer AMT was successful in 64% while the multilayer AMT success rate was 72%. AM gradually dissolved within 3-6 postoperative weeks. Conclusion: AM transplantation facilitates rapid healing of corneal epithelium. In eyes with deep corneal ulcer multilayer technique shows to be better then monolayer procedure. Healing effect could be explained by its ability to reduce inflammation and stimulate epithelial cell regrowth.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA