Pregled bibliografske jedinice broj: 490849
New Developments & Opportunities in Local and Systemic Oral Mucosal Drug Delivery
New Developments & Opportunities in Local and Systemic Oral Mucosal Drug Delivery // Advanced drugs delivery reviews, 64 (2012), 1; 16-28 doi:10.1016/j.addr.2011.02.008 (recenziran, pregledni rad, stručni)
CROSBI ID: 490849 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
New Developments & Opportunities in Local and Systemic Oral Mucosal Drug Delivery
Autori
Hearnden, Vanessa ; Sankar, Vidya ; Hull, Katrusha ; Vidović Juras, Danica ; Greenberg, Martin ; Kerr, Ross A. ; Lockhart, Peter B. ; Patton, Lauren L. ; Porter, Stephen ; Thornhill, Martin
Izvornik
Advanced drugs delivery reviews (0169-409X) 64
(2012), 1;
16-28
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, stručni
Ključne riječi
oral mucosa; drug delivery technology; trans-mucosal; local drug delivery; systemic drug delivery; formulations; targeting; mucoadhesives; polymersomes
Sažetak
The oral mucosa's accessibility, excellent blood supply, by-pass of hepatic first-pass metabolism, rapid repair and permeability profile make it an attractive site for local and systemic drug delivery. Technological advances in mucoadhesives, sustained drug release, permeability enhancers and drug delivery vectors are increasing the efficient delivery of drugs to treat oral and systemic diseases. When treating oral diseases, these advances result in enhanced therapeutic efficacy, reduced drug wastage and the prospect of using biological agents such as genes, peptides and antibodies. These technologies are also increasing the repertoire of drugs that can be delivered across the oral mucosa to treat systemic diseases. Trans-mucosal delivery is now a favoured route for non-parenteral administration of emergency drugs and drugs where a rapid onset of action is required. Furthermore, advances in drug delivery technology are bringing closer the possibility of transmucosal systemic delivery of biological agents.
Izvorni jezik
Engleski
Znanstvena područja
Dentalna medicina, Farmacija
POVEZANOST RADA
Projekti:
065-0650445-0485 - Salivarni markeri oralnih bolesti i njihova primjena (Vučićević Boras, Vanja, MZOS ) ( CroRIS)
Ustanove:
Stomatološki fakultet, Zagreb,
Klinički bolnički centar Zagreb
Profili:
Danica Vidović Juras
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
Uključenost u ostale bibliografske baze podataka::
- BIOSIS Previews (Biological Abstracts)
- Chemical Engineering and Biotechnology Abstracts
- EMBASE (Excerpta Medica)
- International Pharmaceutical Abstracts (IPA)
- MEDLINE
- BIOBASE, Scopus