Naslov
Neonatal Outcome of IVF Singletons versus Naturally Conceived in Women Aged 35 Years and over

Autori
Tomić, Vlatka ; Tomić, Jozo.

Izvornik
Archives of gynecology and obstetrics (0932-0067) 284 (2011); 1411-1416

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
advanced maternal age ; in vitro fertilization ; mode of delivery ; neonatal outcome.

Sažetak
Purpose To compare the delivery and neonatal outcome of IVF singleton pregnancies with those conceived spontaneously in primiparous women ≥35 years of age. Methods Data were collected by the hospital’s obstetrics and pediatric staff at the time of examination, hospitalization, delivery and discharge. A total of 283 women with IVF singleton deliveries were matched according to ethnicity, age, gravidity, smoking habits, body mass index, weight gain in pregnancy, site and time of delivery with consecutive 283 women conceived spontaneously. Outcome measures were mode of delivery, birth weight, preterm birth, chromosomal and/or congenital abnormalities and perinatal mortality. Results Caesarean deliveries rates were significantly higher among IVF singletons, as well as preterm birth rate. No difference was found in the chromosomal and/or congenital abnormalities, perinatal mortality or the birth weight records (SGA, VLBW, LBW and LGA). However, average gestational birth weight was lower among infants conceived after IVF. Conclusions Singleton IVF pregnancies in women aged 35 and above have increased risk associated with preterm births, and infants of lower average birth weight. However, delivery complications, number of infants with low or very low birth weight, small or large birth weight for appropriate gestation and overall rate of congenital abnormalities did not differ from those of the spontaneous conceptions.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA