Pregled bibliografske jedinice broj: 488026
Pathological aspects of lipid peroxidation
Pathological aspects of lipid peroxidation // Free radical research, 44 (2010), 10; 1125-1171 doi:10.3109/10715762.2010.498478 (međunarodna recenzija, pregledni rad, znanstveni)
CROSBI ID: 488026 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Pathological aspects of lipid peroxidation
Autori
Negre-Salvayre, Anne ; Auge, Nathalie ; Ayala, Victoria ; Basaga, Huveyda ; Boada, Jordi ; Brenke, Rainer ; Chapple, Sarah ; Cohen, Guy ; Feher, Janos ; Grune, Tilman ; Lengyel, Gabriella ; Mann, Giovanni E. ; Pamplona, Reinald ; Poli, Giuseppe ; Portero-Otin, Manuel ; Riahi, Yael ; Salvayre, Robert ; Sasson, Shlomo ; Serrano, Jose ; Shamni, Ofer ; Siems, Werner ; Siow, Richard C. M. ; Wiswedel, Ingrid ; Žarković, Kamelija ; Žarković, Neven
Izvornik
Free radical research (1071-5762) 44
(2010), 10;
1125-1171
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni
Ključne riječi
oxidative stress; oxidative homeostasis; ROS; lipid peroxidation; 4-Hydroxynonenal; neurodegenerative diseases; Alzheimer's disease; Parkinson's disease; liver disease; atherosclerosis; redox equilibrium; cell signalling; oxidized phospholipids; oxysterol; diabetes; 4-hydroxydodecadienal; pre-eclampsia; HELLP syndrome; IUGR; glutathione; redox signaling; Nrf2; antioxidant enzymes; foetal endothelium; renal diseases; lymphoedema; hyperglycaemia; advanced glycation end-products; cancer
Sažetak
Lipid peroxidation (LPO) product accumulation in human tissues is a major cause of tissular and cellular dysfunction that plays a major role in ageing and most age-related and oxidative stress-related diseases. The current evidence for the implication of LPO in pathological processes is discussed in this review. New data and literature review are provided evaluating the role of LPO in the pathophysiology of ageing and classically oxidative stress-linked diseases, such as neurodegenerative diseases, diabetes and atherosclerosis (the main cause of cardiovascular complications). Striking evidences implicating LPO in foetal vascular dysfunction occurring in pre-eclampsia, in renal and liver diseases, as well as their role as cause and consequence to cancer development are addressed.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Projekti:
098-0982464-2519 - Lipidi, slobodni radikali i njihovi glasnici u integrativnoj onkologiji (Žarković, Neven, MZOS ) ( CroRIS)
108-0000000-0028 - Oksidacijski stres i tumori središnjeg živčanog sustava (Žarković, Kamelija, MZOS ) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb,
Medicinski fakultet, Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE