Naslov
Natural and synthetic antioxidants – an updated overview

Autori
Augustyniak, Agnieszka ; Bartosz, Grzegorz ; Čipak, Ana ; Duburs, Gunars ; Horakova, Lubica ; Luczaj, Wojciech ; Majekova, Magdalena ; Odysseos, Andreani D. ; Rackova, Lucia ; Skrzydlewska, Elzbieta ; Stefek, Milan ; , Štrosova, Miriam, Tirzitis, Gunars ; Rimantas Venskutonis, Petras Rimantas ; Viskupicova, Jana ; Vraka, Panagiota S. ; Žarković, Neven

Izvornik
Free radical research (1071-5762) 44 (2010), 10; 1216-1262

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
antioxidants ; dihydropyridine derivatives ; free radicals ; lipid peroxidation ; oxidative stress polyphenol ; reactive oxygen spacies ; selenium ; stobadine ; tea ; tocopherol

Sažetak
The current understanding of the complex role of ROS in the organism and pathological sequelae of oxidative stress points to the necessity of comprehensive studies of antioxidant reactivities and interactions with cellular constituents. Studies of antioxidants performed within the COST B-35 action has concerned the search for new natural antioxidants, synthesis of new antioxidant compounds and evaluation and elucidation of mechanisms of action of both natural and synthetic antioxidants. Representative studies presented in the review concern antioxidant properties of various kinds of tea, the search for new antioxidants of herbal origin, modifi cation of tocopherols and their use in combination with selenium and properties of two promising groups of synthetic antioxidants: derivatives of stobadine and derivatives of 1, 4-dihydropyridine.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Temeljne medicinske znanosti

POVEZANOST RADA