Pregled bibliografske jedinice broj: 486846
Characterization and quantification of flavonoid aglycones and phenolic acids in the hydrolyzed methanolic extract of Caucalis platycarpos using HPLC-DAD-MS/MS
Characterization and quantification of flavonoid aglycones and phenolic acids in the hydrolyzed methanolic extract of Caucalis platycarpos using HPLC-DAD-MS/MS // Chemistry of natural compounds, 47 (2011), 1; 27-32 doi:10.1007/s10600-011-9823-6 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 486846 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Characterization and quantification of flavonoid aglycones and phenolic acids in the hydrolyzed methanolic extract of Caucalis platycarpos using HPLC-DAD-MS/MS
Autori
Plazonić, Ana ; Maleš, Željan ; Mornar, Ana ; Nigović, Biljana ; Kujundžić, Nikola
Izvornik
Chemistry of natural compounds (0009-3130) 47
(2011), 1;
27-32
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Caucalis platycarpos L.; flavonoid aglycones; phenolic acids; HPLC-DAD-MS
Sažetak
The water extract of burr parsley (Caucalis platycarpos L.) showed remarkable antitumor activity in rats and mice. Phenolic compounds, including phenolic acids and flavonoids, are considered to be the major bioactive compounds. The aim of this work was to develop a reverse phase HPLC-DAD method for the simultaneous quantification of flavonoid aglycones and phenolic acids, and HPLC-DAD-MS/MS method for structural characterization of phenolic compounds, obtained after hydrolysis of C. platycarpos methanolic extract. Caffeic acid was the predominant phenolic acid, and luteolin was the predominant flavonoid aglycone. The optimized and validated method for the determination of the five phenolic acids and four flavonoid aglycones ensured the reliable results and could be used for the quality control of raw plant material.
Izvorni jezik
Engleski
Znanstvena područja
Kemija, Farmacija
POVEZANOST RADA
Projekti:
006-0061117-1239 - Farmakobotanička i kemijska karakterizacija cvjetnica hrvatske flore (Maleš, Željan, MZOS ) ( CroRIS)
006-0061117-1240 - Istraživanje novih metoda u analitici ljekovitih i bioaktivnih tvari (Nigović, Biljana, MZOS ) ( CroRIS)
006-0061117-1243 - Interakcije galija(III) i željeza(III) s antiproliferativnim lijekovima (Kujundžić, Nikola, MZOS ) ( CroRIS)
Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb
Profili:
Nikola Kujundžić
(autor)
Biljana Nigović
(autor)
Ana Mornar Turk
(autor)
Ana Plazonić
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus