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Pregled bibliografske jedinice broj: 486846

Characterization and quantification of flavonoid aglycones and phenolic acids in the hydrolyzed methanolic extract of Caucalis platycarpos using HPLC-DAD-MS/MS


Plazonić, Ana; Maleš, Željan; Mornar, Ana; Nigović, Biljana; Kujundžić, Nikola
Characterization and quantification of flavonoid aglycones and phenolic acids in the hydrolyzed methanolic extract of Caucalis platycarpos using HPLC-DAD-MS/MS // Chemistry of natural compounds, 47 (2011), 1; 27-32 doi:10.1007/s10600-011-9823-6 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 486846 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Characterization and quantification of flavonoid aglycones and phenolic acids in the hydrolyzed methanolic extract of Caucalis platycarpos using HPLC-DAD-MS/MS

Autori
Plazonić, Ana ; Maleš, Željan ; Mornar, Ana ; Nigović, Biljana ; Kujundžić, Nikola

Izvornik
Chemistry of natural compounds (0009-3130) 47 (2011), 1; 27-32

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Caucalis platycarpos L.; flavonoid aglycones; phenolic acids; HPLC-DAD-MS

Sažetak
The water extract of burr parsley (Caucalis platycarpos L.) showed remarkable antitumor activity in rats and mice. Phenolic compounds, including phenolic acids and flavonoids, are considered to be the major bioactive compounds. The aim of this work was to develop a reverse phase HPLC-DAD method for the simultaneous quantification of flavonoid aglycones and phenolic acids, and HPLC-DAD-MS/MS method for structural characterization of phenolic compounds, obtained after hydrolysis of C. platycarpos methanolic extract. Caffeic acid was the predominant phenolic acid, and luteolin was the predominant flavonoid aglycone. The optimized and validated method for the determination of the five phenolic acids and four flavonoid aglycones ensured the reliable results and could be used for the quality control of raw plant material.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Farmacija



POVEZANOST RADA


Projekti:
006-0061117-1239 - Farmakobotanička i kemijska karakterizacija cvjetnica hrvatske flore (Maleš, Željan, MZOS ) ( CroRIS)
006-0061117-1240 - Istraživanje novih metoda u analitici ljekovitih i bioaktivnih tvari (Nigović, Biljana, MZOS ) ( CroRIS)
006-0061117-1243 - Interakcije galija(III) i željeza(III) s antiproliferativnim lijekovima (Kujundžić, Nikola, MZOS ) ( CroRIS)

Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb

Poveznice na cjeloviti tekst rada:

doi www.springerlink.com

Citiraj ovu publikaciju:

Plazonić, Ana; Maleš, Željan; Mornar, Ana; Nigović, Biljana; Kujundžić, Nikola
Characterization and quantification of flavonoid aglycones and phenolic acids in the hydrolyzed methanolic extract of Caucalis platycarpos using HPLC-DAD-MS/MS // Chemistry of natural compounds, 47 (2011), 1; 27-32 doi:10.1007/s10600-011-9823-6 (međunarodna recenzija, članak, znanstveni)
Plazonić, A., Maleš, Ž., Mornar, A., Nigović, B. & Kujundžić, N. (2011) Characterization and quantification of flavonoid aglycones and phenolic acids in the hydrolyzed methanolic extract of Caucalis platycarpos using HPLC-DAD-MS/MS. Chemistry of natural compounds, 47 (1), 27-32 doi:10.1007/s10600-011-9823-6.
@article{article, author = {Plazoni\'{c}, Ana and Male\v{s}, \v{Z}eljan and Mornar, Ana and Nigovi\'{c}, Biljana and Kujund\v{z}i\'{c}, Nikola}, year = {2011}, pages = {27-32}, DOI = {10.1007/s10600-011-9823-6}, keywords = {Caucalis platycarpos L., flavonoid aglycones, phenolic acids, HPLC-DAD-MS}, journal = {Chemistry of natural compounds}, doi = {10.1007/s10600-011-9823-6}, volume = {47}, number = {1}, issn = {0009-3130}, title = {Characterization and quantification of flavonoid aglycones and phenolic acids in the hydrolyzed methanolic extract of Caucalis platycarpos using HPLC-DAD-MS/MS}, keyword = {Caucalis platycarpos L., flavonoid aglycones, phenolic acids, HPLC-DAD-MS} }
@article{article, author = {Plazoni\'{c}, Ana and Male\v{s}, \v{Z}eljan and Mornar, Ana and Nigovi\'{c}, Biljana and Kujund\v{z}i\'{c}, Nikola}, year = {2011}, pages = {27-32}, DOI = {10.1007/s10600-011-9823-6}, keywords = {Caucalis platycarpos L., flavonoid aglycones, phenolic acids, HPLC-DAD-MS}, journal = {Chemistry of natural compounds}, doi = {10.1007/s10600-011-9823-6}, volume = {47}, number = {1}, issn = {0009-3130}, title = {Characterization and quantification of flavonoid aglycones and phenolic acids in the hydrolyzed methanolic extract of Caucalis platycarpos using HPLC-DAD-MS/MS}, keyword = {Caucalis platycarpos L., flavonoid aglycones, phenolic acids, HPLC-DAD-MS} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


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