Naslov
Effects of enteral nutrition in moderate to severe acute pancreatitis

Autori
Poropat, Goran ; Štimac, Davor

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Pancreatology 2010 ; 10:308-309 / - Basel : Karger Publishers, 2010, 308-309

Skup
42nd European Pancreatic Club (EPC)

Mjesto i datum
Stockholm, Švedska, 17.06.2010. - 19.06.2010

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Enteral nutrition; acute pancreatitis; complications; mortality

Sažetak
Introduction: Nutritional support as enteral preparations is thought to have positive effects on outcome of acute pancreatitis. However, only few trials performed on rather small number of patients showed no statistically significant effects on complications and mortality. Objectives: To determine beneficial and harmful effects of enteral nutrition administered via a nasojejunal tube in comparison to intravenous fluid replacement without nutritional support in patients with moderate to severe acute pancreatitis. Patients and Methods: Hundred-eleven consecutive patients with acute pancreatitis and APACHE II score ³6 were randomized into one of two groups, enteral nutrition group (group I) and group with no nutritional support (group II). There were no significant differences in age, gender, BMI, etiology and disease severity between groups. Severity of acute pancreatitis was determined by APACHE II and Ranson scoring systems. Patients in group I received daily 105kJ (25kcal)/kg and 1, 5g/kg of proteins, while patients in group II received only fluid replacement with crystalloid solutions. The nasojejunal feeding tube was placed within 24 hours of admission and confirmed radiographically. All cases were assessed by CT between days 5 to 10 after admission and graded according to CTSI classification. Results: Fifty patients were randomized in group I and sixtyone patients in group II. There were no significant differences in local (p = 0, 245) and systemic (p = 0, 305)complications according to Atlanta criteria between the two groups. No significant difference in ICU admission (p = 0, 111) and mortality (p = 0, 743) was found either. Conclusion: Our results could not confirm that nutritional support has beneficial or harmful effects on the outcome of acute pancreatitis.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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