Naslov
Does a correlation exist between electrocardiogram and high plasma digoxin levels in the elderly?

Autori
Duraković, Zijad

Izvornik
Rad Hrvatske akademije znanosti i umjetnosti (1330-5301) 28 (469) (1996); 59-65

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
electrocardiogram; plasma digoxin; elderly

Sažetak
In 147 elderly patients, a significantly elevated plasma digoxin level (2.5 nmol/l or more) correlated with the clinical symptoms and electrocardiogram. The condiction disturbances and arrhythmias, as well as the electrocardiogram P-R interval, P-T-Q-index and corrected Q-T interval were analyzed. In 71 (48%) patients, clinical symptoms of digoxin overdose were observed. Arrhythmias were present in 40% of the patients, conduction disturbances in 42%, while only 18% of the patients were free of these changes. A correlation was found between a high plasma digoxin level and the P-R interval (r = +0.207)as well as between a high plasma digoxin level and the P-T-Q index (r = + 0.394), whereas there was no siginificant correlation between the plasma digoxin level and corrected Q-T interval. No correlation was found between the plasma digoxin level and serum potassium concentration, or between the serum creatinine level and plasma digoxin level, although 52 (35%) patients had chronic renal failure.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

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