Naslov
MADNet: A Web Server for Contextual Analysis and Visualization of High-Throughput Experiments

Autori
Šegota, Igor ; Glažar, Petar ; Vlahoviček, Kristian

Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, znanstveni

Knjiga
Systems Biology for Signaling Networks

Urednik/ci
Choi, Sangdun

Izdavač
Springer

Grad
New York (NY)

Godina
2010

Raspon stranica
660-672

ISBN
978-1-4419-5796-2

Ključne riječi
functional genomics, microarray
(.functional genomics, microarray)

Sažetak
Efficient data integration and visualization represents an important component of any systems biology approach. With large datasets resulting from experiments on a complex biological system it is often impossible to analyze and interpret results one by one – rather, we require tools to help us understand the outcome of our experiment in a broader context and with as much visual information as possible. MADNet, the MicroArray Database Network web server, is a user-friendly data mining and visualization tool with a simple and straightforward interface for rapid analysis of diverse high throughput biological experiment results, such as microarray, phage display or even metagenome analysis. It visually presents experimental results in the context of metabolic and signaling pathways, transcription factors and drug targets through minimal user input, consisting only of the file containing a list of genes and associated expression values. This data is integrated with information extracted from various biological databases such as NCBI nucleotide and protein sequence databanks, metabolic and signaling pathway databases (KEGG), transcription regulation (TRANSFAC©) and drug target database (DrugBank). MADNet is freely available for academic use at http://www.bioinfo.hr/madnet.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Računarstvo

POVEZANOST RADA