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Pregled bibliografske jedinice broj: 470915

A Draft Sequence of the Neandertal Genome

Green, Richard E.; Krause, Johannes; Briggs, Adrian W.; Maricic, Tomislav; Stenzel, Udo; Kircher, Martin; Patterson, Nick; Li, Heng; Zhai, Weiwei; Hsi-Yang Fritz, Markus et al.
A Draft Sequence of the Neandertal Genome // Science, 328 (2010), 5979; 710-722 doi:10.1126/science.1188021 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 470915 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
A Draft Sequence of the Neandertal Genome

Autori
Green, Richard E. ; Krause, Johannes ; Briggs, Adrian W. ; Maricic, Tomislav ; Stenzel, Udo ; Kircher, Martin ; Patterson, Nick ; Li, Heng ; Zhai, Weiwei ; Hsi-Yang Fritz, Markus ; Hansen, Nancy F. ; Durand, Eric Y. ; Malaspinas, Anna-Sapfo ; Jensen, Jeffrey D. ; Marques-Bonet, Tomas ; Alkan, Can ; Prüfer, Kay ; Meyer, Matthias ; Burbano, Hernán A. ; Good, Jeffrey M. ; Schultz, Rigo ; Aximu-Petri, Ayinuer ; Butthof, Anne ; Höber, Barbara ; Höffner, Barbara ; Siegemund, Madlen ; Weihmann, Antje ; Nusbaum, Chad ; Lander, Eric S. ; Russ, Carsten ; Novod, Nathaniel ; Affourtit, Jason ; Egholm, Michael ; Verna, Christine ; Rudan, Pavao ; Brajković, Dejana ; Kućan, Željko ; Gušić Ivan ; Doronichev, Vladimir B. ; Golovanova, Liubov V. ; Lalueza-Fox, Carles ; de la Rasilla, Marco ; Fortea, Javier ; Rosas, Antonio ; Schmitz, Ralf W. ; Johnson, Philip L. F. ; Eichler, Evan E. ; Falush, Daniel ; Birney, Ewan ; Mullikin, James C. ; Slatkin, Montgomery ; Nielsen, Rasmus ; Kelso, Janet ; Lachmann, Michael ; Reich, David ; Pääbo, Svante

Izvornik
Science (0036-8075) 328 (2010), 5979; 710-722

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
neandertal genome ; draft sequence

Sažetak
Neandertals, the closest evolutionary relatives of present-day humans, lived in large parts of Europe and western Asia before disappearing 30, 000 years ago. We present a draft sequence of the Neandertal genome composed of more than 4 billion nucleotides from three individuals. Comparisons of the Neandertal genome to the genomes of five present- day humans from different parts of the world identify a number of genomic regions that may have been affected by positive selection in ancestral modern humans, including genes involved in metabolism and in cognitive and skeletal development. We show that Neandertals shared more genetic variants with present-day humans in Eurasia than with present-day humans in sub- Saharan Africa, suggesting that gene flow from Neandertals into the ancestors of non- Africans occurred before the divergence of Eurasian groups from each other.

Izvorni jezik
Engleski

Znanstvena područja
Geologija



POVEZANOST RADA

Projekti:
MZOS-101-2690680-2270 - Korelacija paleolitika mezolitika i neolitika kontinentalne i primorske Hrvatske (Brajković, Dejana, MZOS ) ( CroRIS)
MZOS-196-1962766-2751 - Populacijska struktura Hrvatske - antropogenetički pristup (Rudan, Pavao, MZOS ) ( CroRIS)

Ustanove:
Hrvatska akademija znanosti i umjetnosti,
Institut za antropologiju

Profili:

Avatar Url Dejana Brajković (autor)

Avatar Url Ivan Gušić (autor)

Avatar Url Željko Kućan (autor)

Avatar Url Pavao Rudan (autor)

Poveznice na cjeloviti tekst rada:

doi www.science.org

Citiraj ovu publikaciju:

Green, Richard E.; Krause, Johannes; Briggs, Adrian W.; Maricic, Tomislav; Stenzel, Udo; Kircher, Martin; Patterson, Nick; Li, Heng; Zhai, Weiwei; Hsi-Yang Fritz, Markus et al.
A Draft Sequence of the Neandertal Genome // Science, 328 (2010), 5979; 710-722 doi:10.1126/science.1188021 (međunarodna recenzija, članak, znanstveni)
Green, R., Krause, J., Briggs, A., Maricic, T., Stenzel, U., Kircher, M., Patterson, N., Li, H., Zhai, W. & Hsi-Yang Fritz, M. (2010) A Draft Sequence of the Neandertal Genome. Science, 328 (5979), 710-722 doi:10.1126/science.1188021.
@article{article, author = {Green, Richard E. and Krause, Johannes and Briggs, Adrian W. and Maricic, Tomislav and Stenzel, Udo and Kircher, Martin and Patterson, Nick and Li, Heng and Zhai, Weiwei and Hsi-Yang Fritz, Markus and Hansen, Nancy F. and Durand, Eric Y. and Malaspinas, Anna-Sapfo and Jensen, Jeffrey D. and Marques-Bonet, Tomas and Alkan, Can and Pr\"{u}fer, Kay and Meyer, Matthias and Burbano, Hern\'{a}n A. and Good, Jeffrey M. and Schultz, Rigo and Aximu-Petri, Ayinuer and Butthof, Anne and H\"{o}ber, Barbara and H\"{o}ffner, Barbara and Siegemund, Madlen and Weihmann, Antje and Nusbaum, Chad and Lander, Eric S. and Russ, Carsten and Novod, Nathaniel and Affourtit, Jason and Egholm, Michael and Verna, Christine and Rudan, Pavao and Brajkovi\'{c}, Dejana and Ku\'{c}an, \v{Z}eljko and Doronichev, Vladimir B. and Golovanova, Liubov V. and Lalueza-Fox, Carles and de la Rasilla, Marco and Fortea, Javier and Rosas, Antonio and Schmitz, Ralf W. and Johnson, Philip L. F. and Eichler, Evan E. and Falush, Daniel and Birney, Ewan and Mullikin, James C. and Slatkin, Montgomery and Nielsen, Rasmus and Kelso, Janet and Lachmann, Michael and Reich, David and P\"{a}\"{a}bo, Svante}, year = {2010}, pages = {710-722}, DOI = {10.1126/science.1188021}, keywords = {neandertal genome, draft sequence}, journal = {Science}, doi = {10.1126/science.1188021}, volume = {328}, number = {5979}, issn = {0036-8075}, title = {A Draft Sequence of the Neandertal Genome}, keyword = {neandertal genome, draft sequence} }
@article{article, author = {Green, Richard E. and Krause, Johannes and Briggs, Adrian W. and Maricic, Tomislav and Stenzel, Udo and Kircher, Martin and Patterson, Nick and Li, Heng and Zhai, Weiwei and Hsi-Yang Fritz, Markus and Hansen, Nancy F. and Durand, Eric Y. and Malaspinas, Anna-Sapfo and Jensen, Jeffrey D. and Marques-Bonet, Tomas and Alkan, Can and Pr\"{u}fer, Kay and Meyer, Matthias and Burbano, Hern\'{a}n A. and Good, Jeffrey M. and Schultz, Rigo and Aximu-Petri, Ayinuer and Butthof, Anne and H\"{o}ber, Barbara and H\"{o}ffner, Barbara and Siegemund, Madlen and Weihmann, Antje and Nusbaum, Chad and Lander, Eric S. and Russ, Carsten and Novod, Nathaniel and Affourtit, Jason and Egholm, Michael and Verna, Christine and Rudan, Pavao and Brajkovi\'{c}, Dejana and Ku\'{c}an, \v{Z}eljko and Doronichev, Vladimir B. and Golovanova, Liubov V. and Lalueza-Fox, Carles and de la Rasilla, Marco and Fortea, Javier and Rosas, Antonio and Schmitz, Ralf W. and Johnson, Philip L. F. and Eichler, Evan E. and Falush, Daniel and Birney, Ewan and Mullikin, James C. and Slatkin, Montgomery and Nielsen, Rasmus and Kelso, Janet and Lachmann, Michael and Reich, David and P\"{a}\"{a}bo, Svante}, year = {2010}, pages = {710-722}, DOI = {10.1126/science.1188021}, keywords = {neandertal genome, draft sequence}, journal = {Science}, doi = {10.1126/science.1188021}, volume = {328}, number = {5979}, issn = {0036-8075}, title = {A Draft Sequence of the Neandertal Genome}, keyword = {neandertal genome, draft sequence} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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