Pregled bibliografske jedinice broj: 469769
Sex differences in the reactivity of rats and mice to administration of picrotoxin
Sex differences in the reactivity of rats and mice to administration of picrotoxin // Periodicum biologorum, 87 (1985), 3; 434-434 (podatak o recenziji nije dostupan, članak, znanstveni)
CROSBI ID: 469769 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Sex differences in the reactivity of rats and mice to administration of picrotoxin
Autori
Peričić, Danka ; Manev, Hari
Izvornik
Periodicum biologorum (0031-5362) 87
(1985), 3;
434-434
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Sex differences ; Picrotoxin ; Convulsions ; Rats ; Mice
Sažetak
The results demonstrated that female rats are more sensitive to picrotoxin (a non-competitive antagonist of GABA-A receptors) than males. This was shown by a higher incidence of convulsions and death in female than in male rats following the administration of equal doses of picrotoxin. A totally opposite sex related difference was obtained in mice, since male mice were more sensitive to picrotoxin than female mice.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Ustanove:
Institut "Ruđer Bošković", Zagreb
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