Naslov
Single Nucleotide Polymorphisms and Health Behaviours Related to Obesity – Trawling the Evidence in the Prospect of Personalised Prevention

Autori
Fišter, Kristina ; Polašek, Ozren ; Vuletić, Silvije ; Kern, Josipa

Izvornik
Studies in health technology and informatics (0926-9630) 150 (2009); 762-766

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
cardiovascular diseases; obesity; genomics; single nucleotide

Sažetak
Efforts aimed at primary and secondary prevention of cardiovascular diseases, the major killer of contemporary adult populations, largely rely on modification of risk behaviours related to smoking, physical activity, dietary intake, and alcohol consumption, and also control of obesity and hypertension, the interim risk states between health and disease. We propose that the extent to which the gene x ‘obesogenic’ environment interaction depends on associations between particular single nucleotide polymorphisms (SNPs) and behavioural risk factors for overweight or obesity determines opportunities for novel, personalised preventive interventions. We systematically searched for SNPs that might be of interest for this postulate, and we present various SNPs that have been shown to be associated with overweight or obesity and behavioural risk factors for developing these traits, and thus hold promise for future design of personalised preventive interventions.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita, Informacijske i komunikacijske znanosti

POVEZANOST RADA