Pregled bibliografske jedinice broj: 461640
Non-linear Optimization of Parameters in Michaelis-Menten Kinetics
Non-linear Optimization of Parameters in Michaelis-Menten Kinetics // Croatica chemica acta, 78 (2005), 4; 519-523 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 461640 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Non-linear Optimization of Parameters in Michaelis-Menten Kinetics
Autori
Jeričević, Željko ; Kušter, Željko
Izvornik
Croatica chemica acta (0011-1643) 78
(2005), 4;
519-523
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Michaelis-Menten; enzyme kinetics; non-linear optimization; data processing; least squares
Sažetak
A novel least squares optimization of parameters in Michaelis-Menten enzyme kinetics has been developed. The method is based on elimination of linear parameter from so called normal equations which transforms a non-linear, two-parameter optimization problem into one of finding a root of non-linear equation. The algorithm is simple and has guaranteed convergence with initial guess of zero for KM. Data set from literature is used to illustrate feasibility of the method and accuracy of the solution in comparison with linearization methods and general optimization technique.
Izvorni jezik
Engleski
Znanstvena područja
Kemija, Biologija
POVEZANOST RADA
Ustanove:
Medicinski fakultet, Rijeka,
Institut "Ruđer Bošković", Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
Uključenost u ostale bibliografske baze podataka::
- CA Search (Chemical Abstracts)
