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Pregled bibliografske jedinice broj: 460155

Analysis of the impact of early surgery on in-hospital mortality of native valve endocarditis: use of propensity score and instrumental variable methods to adjust for treatment-selection bias.

Lalani, T.; Cabell, C.H.; Benjamin, D.K.; Lasca, O.; Naber, C.; Fowler V.G. Jr.; Corey, G.R.; Chu, V.H.; Fenely, M.; Pachirat, O. et al.
Analysis of the impact of early surgery on in-hospital mortality of native valve endocarditis: use of propensity score and instrumental variable methods to adjust for treatment-selection bias. // Circulation, 121 (2010), 8; 1005-1013 doi:10.1161/CIRCULATIONAHA.109.864488 (međunarodna recenzija, članak, znanstveni)

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Naslov
Analysis of the impact of early surgery on in-hospital mortality of native valve endocarditis: use of propensity score and instrumental variable methods to adjust for treatment-selection bias.

Autori
Lalani, T. ; Cabell, C.H. ; Benjamin, D.K. ; Lasca, O. ; Naber, C. ; Fowler V.G. Jr. ; Corey, G.R. ; Chu, V.H. ; Fenely, M. ; Pachirat, O. ; Tan, R.S. ; Watkin, R. ; Ionac, A. ; Moreno, A. ; Mestres, C.A. ; Casabé, J. ; Chipigina, N. ; Eisen, D.P. ; Spelman, D. ; Delahaye, F. ; Peterson, G. ; Olaison, L. ; Wang, A ; International Collaboration on Endocarditis-Prospective Cohort Study (ICE-PCS) Investigators: ... ; Baršić, Bruno ; Vincelj, Josip ; Bukovski, Suzana ; Krajinović, Vladimir ; ...

Izvornik
Circulation (0009-7322) 121 (2010), 8; 1005-1013

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
native valve endocarditis; NVE; surgery

Sažetak
The impact of early surgery on mortality in patients with native valve endocarditis (NVE) is unresolved. This study sought to evaluate valve surgery compared with medical therapy for NVE and to identify characteristics of patients who are most likely to benefit from early surgery. Using a prospective, multinational cohort of patients with definite NVE, the effect of early surgery on in-hospital mortality was assessed by propensity-based matching adjustment for survivor bias and by instrumental variable analysis. Patients were stratified by propensity quintile, paravalvular complications, valve perforation, systemic embolization, stroke, Staphylococcus aureus infection, and congestive heart failure. Of the 1552 patients with NVE, 720 (46%) underwent early surgery and 832 (54%) were treated with medical therapy. Compared with medical therapy, early surgery was associated with a significant reduction in mortality in the overall cohort (12.1% [87/720] versus 20.7% [172/832]) and after propensity-based matching and adjustment for survivor bias (absolute risk reduction [ARR] -5.9%, P<0.001). With a combined instrument, the instrumental-variable-adjusted ARR in mortality associated with early surgery was -11.2% (P<0.001). In subgroup analysis, surgery was found to confer a survival benefit compared with medical therapy among patients with a higher propensity for surgery (ARR -10.9% for quintiles 4 and 5, P=0.002) and those with paravalvular complications (ARR -17.3%, P<0.001), systemic embolization (ARR -12.9%, P=0.002), S aureus NVE (ARR -20.1%, P<0.001), and stroke (ARR -13%, P=0.02) but not those with valve perforation or congestive heart failure. Early surgery for NVE is associated with an in-hospital mortality benefit compared with medical therapy alone.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA

Projekti:
108-1080002-0102 - Procjena potrebe i učinkovitosti liječenja teških infekcija u JIM (Baršić, Bruno, MZOS ) ( CroRIS)

Ustanove:
Medicinski fakultet, Zagreb,
Klinika za infektivne bolesti "Dr Fran Mihaljević",
Klinička bolnica "Dubrava"

Profili:

Avatar Url Josip Vincelj (autor)

Avatar Url Suzana Bukovski (autor)

Avatar Url Vladimir Krajinović (autor)

Avatar Url Bruno Baršić (autor)

Poveznice na cjeloviti tekst rada:

doi circ.ahajournals.org

Citiraj ovu publikaciju:

Lalani, T.; Cabell, C.H.; Benjamin, D.K.; Lasca, O.; Naber, C.; Fowler V.G. Jr.; Corey, G.R.; Chu, V.H.; Fenely, M.; Pachirat, O. et al.
Analysis of the impact of early surgery on in-hospital mortality of native valve endocarditis: use of propensity score and instrumental variable methods to adjust for treatment-selection bias. // Circulation, 121 (2010), 8; 1005-1013 doi:10.1161/CIRCULATIONAHA.109.864488 (međunarodna recenzija, članak, znanstveni)
Lalani, T., Cabell, C., Benjamin, D., Lasca, O., Naber, C., Fowler V.G. Jr., Corey, G., Chu, V., Fenely, M. & Pachirat, O. (2010) Analysis of the impact of early surgery on in-hospital mortality of native valve endocarditis: use of propensity score and instrumental variable methods to adjust for treatment-selection bias.. Circulation, 121 (8), 1005-1013 doi:10.1161/CIRCULATIONAHA.109.864488.
@article{article, author = {Lalani, T. and Cabell, C.H. and Benjamin, D.K. and Lasca, O. and Naber, C. and Corey, G.R. and Chu, V.H. and Fenely, M. and Pachirat, O. and Tan, R.S. and Watkin, R. and Ionac, A. and Moreno, A. and Mestres, C.A. and Casab\'{e}, J. and Chipigina, N. and Eisen, D.P. and Spelman, D. and Delahaye, F. and Peterson, G. and Olaison, L. and Wang, A and Bar\v{s}i\'{c}, Bruno and Vincelj, Josip and Bukovski, Suzana and Krajinovi\'{c}, Vladimir}, year = {2010}, pages = {1005-1013}, DOI = {10.1161/CIRCULATIONAHA.109.864488}, keywords = {native valve endocarditis, NVE, surgery}, journal = {Circulation}, doi = {10.1161/CIRCULATIONAHA.109.864488}, volume = {121}, number = {8}, issn = {0009-7322}, title = {Analysis of the impact of early surgery on in-hospital mortality of native valve endocarditis: use of propensity score and instrumental variable methods to adjust for treatment-selection bias.}, keyword = {native valve endocarditis, NVE, surgery} }
@article{article, author = {Lalani, T. and Cabell, C.H. and Benjamin, D.K. and Lasca, O. and Naber, C. and Corey, G.R. and Chu, V.H. and Fenely, M. and Pachirat, O. and Tan, R.S. and Watkin, R. and Ionac, A. and Moreno, A. and Mestres, C.A. and Casab\'{e}, J. and Chipigina, N. and Eisen, D.P. and Spelman, D. and Delahaye, F. and Peterson, G. and Olaison, L. and Wang, A and Bar\v{s}i\'{c}, Bruno and Vincelj, Josip and Bukovski, Suzana and Krajinovi\'{c}, Vladimir}, year = {2010}, pages = {1005-1013}, DOI = {10.1161/CIRCULATIONAHA.109.864488}, keywords = {native valve endocarditis, NVE, surgery}, journal = {Circulation}, doi = {10.1161/CIRCULATIONAHA.109.864488}, volume = {121}, number = {8}, issn = {0009-7322}, title = {Analysis of the impact of early surgery on in-hospital mortality of native valve endocarditis: use of propensity score and instrumental variable methods to adjust for treatment-selection bias.}, keyword = {native valve endocarditis, NVE, surgery} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

Uključenost u ostale bibliografske baze podataka::


  • EMBASE (Excerpta Medica)
  • MEDLINE

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