Naslov
Monocytes in Metabolic Disorders – Opportunities for Flow Cytometry Contributions

Autori
Pandžić Jakšić, Vlatka ; Gizdić, Branimir ; Miletić, Zorana ; Trutin-Ostović, Karmen ; Jakšić, Ozren

Izvornik
Collegium antropologicum (0350-6134) 34 (2010), 1; 319-325

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
monocytes; metabolic disorders; flow cytometry; metabolism; atherosclerosis; obesity

Sažetak
Chronic inflammation has arised as a major underlying cause of atherosclerosis, obesity and diabetes. It is mediated by cells of innate immune system like macrophages but also by their antecedents, circulating monocytes. Roles of monocyte subsets and different markers of monocyte activation in the context of metabolic disorders have been reviewed. Applying cell based approach through flow cytometry in this field has resulted with new understanding of pathophysiologic mechanisms. Possible implications of these insights in diagnosis, prognosis and revealing of therapeutic targets in metabolic disorders remain a challenge for future.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA