Pregled bibliografske jedinice broj: 459171
5-HT2A receptor gene polymorphisms in Croatian subjects with autistic disorder
5-HT2A receptor gene polymorphisms in Croatian subjects with autistic disorder // Psychiatry research, 178 (2010), 3; 556-558 doi:10.1016/j.psychres.2010.04.007 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 459171 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
5-HT2A receptor gene polymorphisms in Croatian subjects with autistic disorder
Autori
Hranilović, Dubravka ; Blažević, Sofia ; Babić, Marina ; Šmurinić, Maja ; Bujas-Petković, Zorana ; Jernej, Branimir
Izvornik
Psychiatry research (0165-1781) 178
(2010), 3;
556-558
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
serotonin ; -1438 A/G ; His452Tyr
Sažetak
Disturbances in expression/function of 5-HT2A receptor are implicated in autism. Association of 5-HT2A receptor gene with autism was studied in Croatian population. Distribution frequencies for alleles, genotypes and haplotypes of -1438 A/G and His452Tyr polymorphisms were compared in samples of 103 autistic and 214 control subjects. Significant overrepresentation of G allele and GG genotype of -1438 A/G polymorphism was observed in group of autistic subjects, supporting possible involvement of 5-HT2A receptor in development of autism.
Izvorni jezik
Engleski
Znanstvena područja
Biologija, Temeljne medicinske znanosti
POVEZANOST RADA
Projekti:
098-1081870-2395 - Serotonergična neurotransmisija: geni, proteini i ponašanje (Štefulj, Jasminka, MZOS ) ( CroRIS)
119-1081870-2396 - Neurobiološka podloga autizma: uloga serotoninskog sustava (Hranilović, Dubravka, MZOS ) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb,
Prirodoslovno-matematički fakultet, Zagreb
Profili:
Sofia Ana Blažević
(autor)
Branimir Jernej
(autor)
Zorana Bujas-Petković
(autor)
Dubravka Hranilović
(autor)
Marina Babić Čač
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- Social Science Citation Index (SSCI)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE