Naslov
Postnatal development of layer IV in fronto-opercular region (Broca`s area)

Autori
Cepanec, Maja ; Judaš, Miloš

Izvornik
Translational Neuroscience (2081-3856) 1 (2010), 1; 24-29

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
cytoarchitectonics ; human cerebral cortex ; inferior frontal gyrus ; opercular area/FCBm ; Triangular area/FDγ

Sažetak
In the adult human fronto-opercular cortex, the grade of granularity of cortical layer IV represents a major architectonic feature for distinguishing the opercular area BA44 (which is typically described as being magnopyramidal and intermedio-granular) from the triangular area BA45 (which is typically described as being magnopyramidal and granular). We analyzed postnatal cytoarchitectonic development of internal granular layer (layer IV) of the fronto-opercular region in 23 brains of newborns, infants and children (age range: 15 days to 15 years) and in one adult brain. We found that: (1) the grade of granularity of layer IV in the fronto-opercular cortex displays a great interindividual variability throughout development as well as in the adult brain ; (2) this variability is much more pronounced in the opercular area BA44 than in the triangular area BA45. Our findings support the classical interpretation provided by Constantin von Economo (von Economo & Koskinas, 1925) according to which BA44/FCBm represents a specialized variant of the wide premotor cortical zone, while BA45/ FDG represents a specialized variant of the typical (associative) frontal granular cortex.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

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