Pregled bibliografske jedinice broj: 45605
Manufacture of semisynthetic cephalosporins
Manufacture of semisynthetic cephalosporins
(1982)
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Naslov
Manufacture of semisynthetic cephalosporins
Autori
Kovačević, Miće ; Herak, Juraj ; Gašpert, Branimir
Broj patenta
GB 2 103 211 B
Godina
1982
Datum patenta
21. 08. 1985.
Nositelj prava
Pliva, HR/YU, Zagreb, Hrvatska
Sažetak
This invention relates to the manufacture of semisynthetic cephalosporin of the formula I, which comprises reacting an N-protected alfa-phenylglycine of the formula II with an N-chlorocarbonyl-sec.-amide of the formula III to form a mixed anhydride of the formula IV, and subjecting the mixed anhydride IV to aminolysis by reaction with an ester of 7-aminodesacetoxy cephalosporanic acid of the formula V.
Izvorni jezik
Engleski