Naslov
Percutaneous ethanol injection in thyroid cancer metastases treatment

Autori
Kusačić Kuna, Sanja ; Tomić Brzac, Hrvojka ; Despot, Marija ; Horvatić Herceg, Gordana ; Dodig, Damir

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
BMUS and EFSUMB Proceedings of the British Medical Ultrasound Society and EFSUMB 21st Euroson Congress, (abstract booklet) 2009, Edinburgh, UK / - Edinburgh, 2009

Skup
21st European Ultrasound Congress

Mjesto i datum
Edinburgh, Ujedinjeno Kraljevstvo, 06.12.2009. - 08.12.2009

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
neck metastases; thyroid cancer; percutaneous ethanol injection

Sažetak
Background and purpose: Percutaneous treatment of metastases by injection of 95% ethanol (PEIT) under ultrasound guidance has been used to treat various neoplasms. The aim of study was to evaluate the efficacy and safety of this method in selected group of patients with limited cervical neck metastases from thyroid cancer. Patients and methods: PEIT was made in a group of patients with high risk of operative complications after repeated surgery and those who preferred not to have surgery. All treated lymph nodes were previously citologically confirmed as malignant. 16 patients (12 women, mean age 62.6 years ; range 26-77 years) presented with solitary metastasis of thyroid cancer in the neck were treated. All patients have undergone total thyroidectomy followed by radioiodine ablation. In ten patients a lateral neck dissection had been performed, and seven of them had been operated several times because of reccurent disease. Four patients had distant metastases, and two patients had a second malignancy that cannot permit another surgery. The volume of ethanol used in treated nodes depends on their size. All treated patients were periodically followed by Color Doppler ultrasound. Results: We noticed a significant reduction of nodal size as well as decrease of thyroglobulin level in great majority of patients, after one or more treatments (nine nodes showed 80 % reduction in size). Two nodes were completely disappeared. In four patients with a more widespread disease and metastases in the lungs and bones satisfactory results were not achieved. No serious adverse events were related to percutaneous ethanol administration. Conclusion: The PEIT is a safe, alternative treatment modality that can be helpfull in reducing disease progression in selected group of patients with recurrent thyroid cancer neck metastases. The method is well received by patients, can be repeated several times and it is less invasive than surgery, with low rate of complications.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA