Molecular alterations of E-cadherin and beta-catenin in brain metastases

Zeljko, Martina; Pećina-Šlaus, Nives; Nikuševa Martić, Tamara; Kušec, Vesna; Beroš, Vili; Tomas, Davor

doi:10.2741/e274

Pregled bibliografske jedinice broj: 452338

Molecular alterations of E-cadherin and beta-catenin in brain metastases

Zeljko, Martina; Pećina-Šlaus, Nives; Nikuševa Martić, Tamara; Kušec, Vesna; Beroš, Vili; Tomas, Davor

Molecular alterations of E-cadherin and beta-catenin in brain metastases // Frontiers in bioscience (Elite ed.), 3 (2011), 2; 616-624 doi:10.2741/e274 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 452338 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Molecular alterations of E-cadherin and beta-catenin in brain metastases

Autori
Zeljko, Martina ; Pećina-Šlaus, Nives ; Nikuševa Martić, Tamara ; Kušec, Vesna ; Beroš, Vili ; Tomas, Davor

Izvornik
Frontiers in bioscience (Elite ed.) (1945-0494) 3 (2011), 2; 616-624

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
E-cadherin (CDH1) ; beta-catenin (CTNNB1) ; brain metastasis ; loss of heterozygosity ; heteroduplex ; image analysis ; immunostaining

Sažetak
In the present study 47 brain metastases were analyzed regarding changes of E-cadherin (CDH1) and beta-catenin (CTNNB1) genes and proteins. Our idea was that the analysis of distant metastases could elucidate the consequence of tumor progression in regard of its mutational complexity.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA

Projekti:
MZOS-108-1081870-1905 - Uloga signalnog puta wnt u tumorigenezi i embriogenezi mozga (Pećina-Šlaus, Nives, MZOS ) ( CroRIS)
MZOS-214-1080229-0163 - Zajednička molekularna osnova etiopatogeneza koštanih poremećaja u ljudi (Kušec, Vesna, MZOS ) ( CroRIS)

Ustanove:
Medicinski fakultet, Zagreb,
Klinički bolnički centar Zagreb

Profili:

Vesna Kušec (autor)