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Pregled bibliografske jedinice broj: 451573

Prognostic factors and outcomes for osteosarcoma : An international collaboration

Pakos, Emilios E.; Nearchou, Andreas D.; Grimer, Robert J.; Koumoullis, Haris D.; Abudu, Adesegun; Bramer, Jos A.M.; Jeys, Lee M.; Franchi, Alessandro; Scoccianti, Guido; Campanacci, Domenico et al.
Prognostic factors and outcomes for osteosarcoma : An international collaboration // European journal of cancer (1990), 45 (2009), 13; 2367-2375 doi:10.1016/j.ejca.2009.03.005 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 451573 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Prognostic factors and outcomes for osteosarcoma : An international collaboration

Autori
Pakos, Emilios E. ; Nearchou, Andreas D. ; Grimer, Robert J. ; Koumoullis, Haris D. ; Abudu, Adesegun ; Bramer, Jos A.M. ; Jeys, Lee M. ; Franchi, Alessandro ; Scoccianti, Guido ; Campanacci, Domenico ; Capanna, Rodolfo ; Aparicio, Jorge ; Tabone, Marie-Dominique ; Holzer, Gerold ; Abdolvaha, Fashid ; Funovics, Philipp ; Dominkus, Martin ; Ilhan, Inci ; Berrak, Su G. ; Patino-Garcia, Ana ; Sierrasesumaga, Luis ; San-Julian, Mikel ; Garraus, Moira ; Petrilli, Antonio Sergio ; Filho, Reynaldo Jesus Garcia ; Macedo, Carla Renata Pacheco Donato ; de Seixas Alves, Maria Teresa ; Seiwerth, Sven ; Nagarajan, Rajaram ; Cripe, Timothy P. ; Ioannidis, John P.A.

Izvornik
European journal of cancer (1990) (0959-8049) 45 (2009), 13; 2367-2375

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
osteosarcoma; clinical predictors; prognosis; survival; metastasis; international collaboration

Sažetak
We aimed to evaluate the prognostic significance of traditional clinical predictors in osteosarcoma through an international collaboration of 10 teams of investigators (2680 patients) who participated. In multivariate models the mortality risk increased with older age, presence of metastatic disease at diagnosis, development of local recurrence when the patient was first seen, use of amputation instead of limb salvage/wide resection, employment of unusual treatments, use of chemotherapeutic regimens other than anthracycline and platinum and use of methotrexate. It was also influenced by the site of the tumour. The risk of metastasis increased when metastatic disease was present at the time the patient was first seen and also increased with use of amputation or unusual treatment combinations or chemotherapy regimens not including anthracycline and platinum. Local recurrence risk was higher in older patients, in those who had local recurrence when first seen and when no anthracycline and platinum were used in chemotherapy. Results were similar when limited to patients seen after 1990 and treated with surgery plus combination chemotherapy. This large-scale international collaboration identifies strong predictors of major clinical outcomes in osteosarcoma.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

Napomena
Rad je kao poster prezentiran na skupu 19th European Congress of Pathology, održanom 06.11.2003., Ljubljana, Slovenija.



POVEZANOST RADA

Projekti:
053-0532264-2260 - Komparativna dijagnostika, morfometrija i analiza tumora ljudi i životinja (Grabarević, Željko, MZOS ) ( CroRIS)
108-1083570-3643 - Kvantitativna analiza i prijenos slike u patologiji (Seiwerth, Sven, MZOS ) ( CroRIS)

Ustanove:
Veterinarski fakultet, Zagreb,
Medicinski fakultet, Zagreb

Profili:

Avatar Url Sven Seiwerth (autor)

Poveznice na cjeloviti tekst rada:

doi www.sciencedirect.com www.sciencedirect.com

Citiraj ovu publikaciju:

Pakos, Emilios E.; Nearchou, Andreas D.; Grimer, Robert J.; Koumoullis, Haris D.; Abudu, Adesegun; Bramer, Jos A.M.; Jeys, Lee M.; Franchi, Alessandro; Scoccianti, Guido; Campanacci, Domenico et al.
Prognostic factors and outcomes for osteosarcoma : An international collaboration // European journal of cancer (1990), 45 (2009), 13; 2367-2375 doi:10.1016/j.ejca.2009.03.005 (međunarodna recenzija, članak, znanstveni)
Pakos, E., Nearchou, A., Grimer, R., Koumoullis, H., Abudu, A., Bramer, J., Jeys, L., Franchi, A., Scoccianti, G. & Campanacci, D. (2009) Prognostic factors and outcomes for osteosarcoma : An international collaboration. European journal of cancer (1990), 45 (13), 2367-2375 doi:10.1016/j.ejca.2009.03.005.
@article{article, author = {Pakos, Emilios E. and Nearchou, Andreas D. and Grimer, Robert J. and Koumoullis, Haris D. and Abudu, Adesegun and Bramer, Jos A.M. and Jeys, Lee M. and Franchi, Alessandro and Scoccianti, Guido and Campanacci, Domenico and Capanna, Rodolfo and Aparicio, Jorge and Tabone, Marie-Dominique and Holzer, Gerold and Abdolvaha, Fashid and Funovics, Philipp and Dominkus, Martin and Ilhan, Inci and Berrak, Su G. and Patino-Garcia, Ana and Sierrasesumaga, Luis and San-Julian, Mikel and Garraus, Moira and Petrilli, Antonio Sergio and Filho, Reynaldo Jesus Garcia and Macedo, Carla Renata Pacheco Donato and de Seixas Alves, Maria Teresa and Seiwerth, Sven and Nagarajan, Rajaram and Cripe, Timothy P. and Ioannidis, John P.A.}, year = {2009}, pages = {2367-2375}, DOI = {10.1016/j.ejca.2009.03.005}, keywords = {osteosarcoma, clinical predictors, prognosis, survival, metastasis, international collaboration}, journal = {European journal of cancer (1990)}, doi = {10.1016/j.ejca.2009.03.005}, volume = {45}, number = {13}, issn = {0959-8049}, title = {Prognostic factors and outcomes for osteosarcoma : An international collaboration}, keyword = {osteosarcoma, clinical predictors, prognosis, survival, metastasis, international collaboration} }
@article{article, author = {Pakos, Emilios E. and Nearchou, Andreas D. and Grimer, Robert J. and Koumoullis, Haris D. and Abudu, Adesegun and Bramer, Jos A.M. and Jeys, Lee M. and Franchi, Alessandro and Scoccianti, Guido and Campanacci, Domenico and Capanna, Rodolfo and Aparicio, Jorge and Tabone, Marie-Dominique and Holzer, Gerold and Abdolvaha, Fashid and Funovics, Philipp and Dominkus, Martin and Ilhan, Inci and Berrak, Su G. and Patino-Garcia, Ana and Sierrasesumaga, Luis and San-Julian, Mikel and Garraus, Moira and Petrilli, Antonio Sergio and Filho, Reynaldo Jesus Garcia and Macedo, Carla Renata Pacheco Donato and de Seixas Alves, Maria Teresa and Seiwerth, Sven and Nagarajan, Rajaram and Cripe, Timothy P. and Ioannidis, John P.A.}, year = {2009}, pages = {2367-2375}, DOI = {10.1016/j.ejca.2009.03.005}, keywords = {osteosarcoma, clinical predictors, prognosis, survival, metastasis, international collaboration}, journal = {European journal of cancer (1990)}, doi = {10.1016/j.ejca.2009.03.005}, volume = {45}, number = {13}, issn = {0959-8049}, title = {Prognostic factors and outcomes for osteosarcoma : An international collaboration}, keyword = {osteosarcoma, clinical predictors, prognosis, survival, metastasis, international collaboration} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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