Pregled bibliografske jedinice broj: 447760
Recognition of single stranded and double stranded DNA / RNA sequences in aqueous medium by small bis-aromatic derivatives
Recognition of single stranded and double stranded DNA / RNA sequences in aqueous medium by small bis-aromatic derivatives // Mini-reviews in medicinal chemistry, 10 (2010), 4; 299-308 doi:10.2174/138955710791330990 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 447760 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Recognition of single stranded and double stranded DNA / RNA sequences in aqueous medium by small bis-aromatic derivatives
Autori
Tumir, Lidija-Marija ; Piantanida, Ivo
Izvornik
Mini-reviews in medicinal chemistry (1389-5575) 10
(2010), 4;
299-308
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
DNA and RNA binding ; bis-intercalation ; macrocyclic bis-intercalation ; intercalator – nucleobase conjugate
Sažetak
The aim of this review is to summarize the most comprehensive results in the field of bis-aromatic compounds targeting DNA and RNA, whereby both aromatic units of small molecule bind to the polynucleotide by the aromatic stacking interactions. The most recent results about structure – DNA/RNA binding affinity, selectivity and biological implications are discussed for bis-intercalators, sterically restricted macrocyclic and threading bis-aromatics and intercalator – nucleobase conjugates.
Izvorni jezik
Engleski
Znanstvena područja
Kemija, Temeljne medicinske znanosti
POVEZANOST RADA
Projekti:
098-0982914-2918 - Dizajn, sinteza i ispitivanje interakcija malih molekula s DNA, RNA i proteinima (Piantanida, Ivo, MZOS ) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
