Pregled bibliografske jedinice broj: 445831
Hydroxyurea and hydroxamic acid derivatives as antitumor drugs
Hydroxyurea and hydroxamic acid derivatives as antitumor drugs // Cancer chematotherapy and pharmacology, 64 (2009), 2; 213-221 doi:10.1007/s00280-009-0991-z (recenziran, pregledni rad, stručni)
CROSBI ID: 445831 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Hydroxyurea and hydroxamic acid derivatives as antitumor drugs
Autori
Šaban, Nina ; Bujak, Maro
Izvornik
Cancer chematotherapy and pharmacology (0344-5704) 64
(2009), 2;
213-221
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, stručni
Ključne riječi
hydroxyurea. hydroxamic acid derivatives; cancer
Sažetak
Hydroxyurea has been used for decades and it is still valuable for the treatment of some types of cancer. It inhibits ribonucleotide reductase (RNR) enzyme known to be crucial in the conversion of ribonucleotides into deoxyribonucleotides. However, nowadays the main focus has shifted to structurally similar hydroxamic acid derivatives that target specific enzymes involved in cancer progression such as histone deacetylasesm, matrix metalloproteinases and also RNR.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Projekti:
098-0982464-2393 - Molekularna obilježja miofibroblasta Dupuytrenove bolesti
125-0982464-2922 - RAZVOJ NOVIH PROLIJEKOVA I LIJEKOVA PROTIV VIRUSA I RAKA (Mintas, Mladen, MZOS ) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb,
Fakultet kemijskog inženjerstva i tehnologije, Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
