Naslov
Cosyntropin for Treatment of Chronic Inflammatory Demyelinating polyneuropathy (CIDP)

Autori
Sepčić, Juraj ; Radolović-Prenc, Lorena ; Rudež, Josip ; Antonelli, Licia ; Škarpa-Prpić, Ingrid ; Perković, Olivio ; Šepić-Grahovac, Dubravka ; Dunatov, Siniša

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Abstracts. Neurologia Croatica 2000; 49 (Suppl.3) / Gubarev, Nikola - Zagreb : Hrvatsko neurološko društvo, 2000, 93-94

Skup
4th Croatian Symposium of Epilepsie, 1st Croatian Congress of Neurophysiology, 1st Croatian Symposium of Neuromuscular Disorders, 2nd Croatian Seminar of Neurophysiology Tehnicians.

Mjesto i datum
Zagreb, Hrvatska, 10.2000

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
Cosyntropin; Chronic Inflammatory Demyelinating polyneuropathy

Sažetak
CIDP is manifested by inflammatory myelin lesion primarily in the roots and proximal segments of peripheral nerves. The cause is not known. Immunological studies suggest that it is, at least partially, a T-cell-mediated disorder. The disease is either chronic of intermittent with exacerbations. CIDP is diagnosed by clinical, electrophysiological, and histopathological findings, as well as cerebrospinal fluid (CSF) analysis. Immunomodulating steroids, plasma-exchange, or intravenous immunoglobulins are considered to be effective treatments. We present a case of the hypertropfic variant of CIDP combined with CNS demyelinization in a patient followed for 29 years. The administration of cosyntropin, a synthetic preparation of adenocorticotropic hormone used primarily to test adrenocortical response or reserve, during relapses has always resulted in excellent remissions. We conclude that cosyntropin has its place in CIDP treatment. The results of its application correlate with those obtaindes with much more exprensive medications and/or procedures.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

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