Pregled bibliografske jedinice broj: 444693
Laser Capture Microdissection and PCR for analysis of HPV Infection
Laser Capture Microdissection and PCR for analysis of HPV Infection // International Workshop on Human Papillomavirus and Consensus Recommendations for Cervical Cancer Prevention and Colposcopy Training / Grce, Magdalena (ur.).
Zagreb: Institut Ruđer Bošković, 2007. str. 44-44 (predavanje, međunarodna recenzija, sažetak, ostalo)
CROSBI ID: 444693 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Laser Capture Microdissection and PCR for analysis of HPV Infection
Autori
Grahovac, Blaženka ; Hadžisejdić, Ita ; Krašević, Maja
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo
Izvornik
International Workshop on Human Papillomavirus and Consensus Recommendations for Cervical Cancer Prevention and Colposcopy Training
/ Grce, Magdalena - Zagreb : Institut Ruđer Bošković, 2007, 44-44
ISBN
978-953-6690-65-7
Skup
International workshop on Human Papillomaviruses and consensus recommendations for cervical cancer prevention & colposcopy training
Mjesto i datum
Dubrovnik, Hrvatska, 18.04.2007. - 21.04.2007
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
HPV; HPV infection; laser capture microdisection; cervical cancer
Sažetak
Human papillomavirus (HPV) infection is considered as one of main factors involved in the pathogenesis of squamous cell carcinoma (SCC) and adenocarcinoma (ADC). Our previous study revealed a high prevalence of high-risk (hr) HPV-DNA in examined cervical lesioons (>90%). HPV-16 predominated in SCC (65%) and HPV-18 in ADC (67.6%). The prevalence of particular hr-HPV types in adenosquamous carcinoma (ADSQ) is controversal as well as the presence of different HPV types within this tumor. Tha aim of this study was to detect hr-HPV DNA and to determine the HPV type in microdissected tissue of 4 cases of cervical adenosquamous carcinoma using lase capture microdissection (P.A.L.M.) followed by DNA extraction and qualitative PCR. Our results confirm the associtaion of certain hr-HPV types to different histological entity of ADSQ and importance of microdissection in molecular diagnostics.
Izvorni jezik
Engleski
