Pregled bibliografske jedinice broj: 441986
PPARγ – A New Concept Of Treatment?
PPARγ – A New Concept Of Treatment? // Diabetologia Croatica, 38 (2009), 2; 23-30 (podatak o recenziji nije dostupan, pregledni rad, stručni)
CROSBI ID: 441986 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
PPARγ – A New Concept Of Treatment?
Autori
Soldo-Jureša, Dragica ; Metelko, Željko
Izvornik
Diabetologia Croatica (0351-0042) 38
(2009), 2;
23-30
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, stručni
Ključne riječi
peroxisome proliferator-activated receptors (PPARs); nuclear receptor; thiazolidinediones; diabetes mellitus
Sažetak
Peroxisome proliferator-activated receptors (PPARs)are ligand-activated transcription factors belonging to the nuclear receptor superfamily, which also includes the steroid and thyroid hormone receptors. PPARs modulate genes that regulate lipid and glucose metabolism and control many cellular and metabolic processes. Three isotypes called PPARα, PPAR β/δ and PPARγ have been identified. Their activity can be modulated by drugs such as fibrates and thiazolidinediones. Understanding the biology and identifying small molecule modulators of the PPARs is an active area of research and may impact chronic diseases such as type 2 diabetes, dyslipidemia, atherosclerosis and the metabolic syndrome.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Ustanove:
Klinika za dijabetes, endokrinologiju i bolesti metabolizma Vuk Vrhovac
Citiraj ovu publikaciju:
Časopis indeksira:
- Scopus
Uključenost u ostale bibliografske baze podataka::
- EMBASE (Excerpta Medica)
