Naslov
Neuron specific enolase (NSE) and S-100 protein immunoreaction in developing human gut and pancreas

Autori
Rode, Bojan ; Lacković, Gordana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
8th International Congress of Histochemistry and Cytochemistry

Mjesto i datum
Sjedinjene Američke Države, 31.07.1988. - 05.08.1988

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
enolase; immunohistochemistry; gut; pancreas; human fetus

Sažetak
NSE and S-100 were immunohistochemically studied by PAP method in pancreas, antrum and intestine of 20 human fetuses during gestation period 16-42 wk and postnatally (6 wk). At 18 wk NSE and S-100 immunoreactivity was more advanced in nerves of pancreas than in still primitive myenteric and submucosal plexus of the gut. In mesenteryc, perlpancreatic and in the gut lymphold cells NSE and S-100 first appeared. By 21 wk of gestation pronounced development of entire enteric nerves had taken place. Numerous NSE and S-100 reactive endocrine cells with various grade of granular density first appeared in antrum and only single cells in duodenum. The volume denslty (Vv) of NSE positive endocrine cells reached by 23 wk 4% of antral epithellum. Adult patterns of distribution of HSE and S-100 in enteric nerves were established at 24 wk of development. At 26 wk Vv of endocrine cells in antrum increased to 7%. The peak of 14% Vv was found in the fetus with postmature birth (42 wk) with a postnataly (6 wk) decrease to 7%. In two test samples the Vv of NSE and S-100 reactive endocrine cells was practically the same accordlng to the stereologlcal point counilng method. In the gut associated lymphoid tissue, nervous elements were clearly detected at 21 wk in addition to HSE and S-100 stained lymphoid cells. The overlapping distribution of HSE and S-100 reactive endocrine cells was not observed in gastroduodenopancreatic system in this study.

Izvorni jezik
Engleski

Znanstvena područja
Biologija

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