Pregled bibliografske jedinice broj: 435856
Gender and speces differencs in the expression of renal OATs and OCTs
Gender and speces differencs in the expression of renal OATs and OCTs // Kongress fuer Nephrologie ; 1. Jahrestagung der Deutschen Gesellschaft fuer Nephrologie
Göttingen, Njemačka, 2009. (pozvano predavanje, nije recenziran, neobjavljeni rad, znanstveni)
CROSBI ID: 435856 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Gender and speces differencs in the expression of renal OATs and OCTs
Autori
Sabolić, Ivan
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni
Skup
Kongress fuer Nephrologie ; 1. Jahrestagung der Deutschen Gesellschaft fuer Nephrologie
Mjesto i datum
Göttingen, Njemačka, 26.09.2009. - 29.09.2009
Vrsta sudjelovanja
Pozvano predavanje
Vrsta recenzije
Nije recenziran
Ključne riječi
organic anion transporters; organic cation transporters; kidney; sex differences
Sažetak
In the mammalian nephron, secretion and/or reabsorption of various endogenous and exogenous organic anions and cations is mediated with specific transporters (OATs and OCTs) localized in the apical or basolateral membrane of the epithelial cells. Our recent immunochemical studies showed that the expresion of various transporters exhibits sex differences in rats and mice, but not in pigs and humans. These data indicate that rodents may not be good models for pharmacological and toxicological studies relevant for humans.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Projekti:
022-0222148-2146 - Bubrežni prijenosnici u sisavaca; spolne razlike i učinci toksičnih metala (Sabolić, Ivan, MZOS ) ( CroRIS)
Ustanove:
Institut za medicinska istraživanja i medicinu rada, Zagreb
Profili:
Ivan Sabolić
(autor)
