Naslov
Vascular cognitive impairment in DM: are prevention and treatment effective?

Autori
Demarin, Vida ; Zavoreo, Iris

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
Abstracts CD-ROM / - , 2009

Skup
Sixth International Congress on Vascular Dementia

Mjesto i datum
Barcelona, Španjolska, 19.11.2009. - 22.11.2009

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
cognitive impairment; vascular; diabetes mellitus

Sažetak
Vascular dementia is caused by progressive atherosclerosis leading to multiple small strokes and subsequent brain damage. Approximately forty percent of dementia cases are attributed to vascular dementia. It is a growing public health concern, because of lack of effective curative treatment options and rising global prevalence. Common risk factors are the same ones for cerebrovascular disease- unmodifiable risk factors: age, gender, genotype, previous myocardial infarction, TIA or stroke and modifiable risk factors: hyperlipidemia, arterial hypertension, smoking, diabetes, obesity, physical inactivity, stress, alcohol, atrial fibrillation. Of patients who suffered stroke, a large proportion either has or is later diagnosed with diabetes (16-24%). Patients with diabetes are at 1.5-3 times the risk of cerebrovascular disease and 1.5 times the risk of dementia. Even patients with metabolic syndrome component have a 1.5 fold increased risk of stroke. Generally, vascular complications of diabetes can be separated into microvascular (diabetic nephropathy, neuropathy and retinopathy) and macrovascular (coronary disease, cerebrovascular disease, peripheral artery disease) complications. The onset of vascular dementia goes unnoticed in the early stages, sometimes symptoms such as cognitive and intellectual impairment as well as carrying out everyday activities may became apparent only in the mid-to-late stages. Impact of risk factors reduction, genetics and possible pharmaceutical treatment of vascular dementia should be evaluated through results of the clinical trials and meta analyses.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA