Naslov
Esomeprasole versus Pantoprazole for healing erosive oesophagitis

Autori
Včev, Aleksandar ; Begić, Ivana ; Ostojić, Rajko ; Jurčić, Dragan ; Božić, Dubravko ; Soldo, Ivan ; Gmajnić, Rudika ; Kondža, Goran ; Khaznadar, E. ; Mićunović, Nikola

Izvornik
Collegium Antropollogicum (1330-4917) 30 (2006), 3; 519-522

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
GERD; esomeprazole; pantoprazole

Sažetak
The aim of this study was to compare the efficacy of esomeprazole and pantoprazole with regard to healing and relief from gastroesophageal reflux disease-related symptoms. In this multicentre, randomized, single-blind study 180 patients ( ITT population ) diagnosed with endoscopically proven GERD grade A, B, C received esomeprazole ( 40 mg once daily (o.d), n=90 ) or pantoprazole ( 40 mg o.d., n= 90 ). Healing and relief from GERD-related symptoms were assessed at first and final visit ( after 4 or 8 weeks of treatment ). Esomeprazole 40 mg provided significantly greater healing than pantoprazole 40 mg after 4 weeks of treatment in patients with EE ( 77.8 % vs. 91.1 % ). The proportion of heartburn-free days was similar in patients treated with esomeprazole and to those treated with pantoprazole.

Izvorni jezik
Engleski

POVEZANOST RADA