Pregled bibliografske jedinice broj: 42742
Spontaneous BHV1 recombinants in which the gI/gE/US9 region is replaced by a duplication/inversion of the US1.5/US2 region
Spontaneous BHV1 recombinants in which the gI/gE/US9 region is replaced by a duplication/inversion of the US1.5/US2 region // Archives of Virology, 144 (1999), 8; 1527-1537 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 42742 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Spontaneous BHV1 recombinants in which the gI/gE/US9 region is replaced by a duplication/inversion of the US1.5/US2 region
Autori
Rijsewijk, F.A.M. ; Verschuren, S.B.E. ; Madić, Josip ; Ruuls, R.C. ; Renaud, P. ; van Oirschot, J.T.
Izvornik
Archives of Virology (0304-8608) 144
(1999), 8;
1527-1537
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Simplex virus type-1; E deletion mutant; Bovine herpesvirus-1; Glycoprotein-e; Sequences; Virulence; Lacking; Repeats; Genome; Calves
Sažetak
In a bovine herpesvirus 1 (BHV1) vaccine strain, a spontaneous BHV1 mutant (Za) was found that arose from a recombination between two isometric forms of the BHV 1 genome. In this Za mutant one end of the U-S region, containing part of the US1.5 gene, was found duplicated in ana inverted orientation at the other end of the U-S region. The nucleotide sequences of the recombination points of both recombinants were determined and compared. The implications for the use of BHV1 gE deletion mutants as marker or diva vaccines are discussed.
Izvorni jezik
Engleski
Znanstvena područja
Veterinarska medicina
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