Naslov
Laccase-Catalyzed L-DOPA Oxidation on Macro and Microreactor Scale

Autori
Tišma, Marina ; Zelić, Bruno ; Vasić-Rački, Đurđa ; Žnidaršič-Plazl, P. ; Plazl. I.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
6th World Congress on Oxidation Catalysis: Towards an integrated approach in innovation and development / - Lille, 2009, 286-287

Skup
6th World Congress on Oxidation Catalysis

Mjesto i datum
Lille, Francuska, 05.10.2009

Vrsta sudjelovanja
Pozvano predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
laccase ; L-DOPA ; microreactor ; modelling

Sažetak
Enzymatic oxidation of 3, 4-dihydroxyphenyl-L- alanine (L-DOPA) with laccase from Trametes versicolor was investigated in a batch laboratory-scale reactor and in a continuously operated microreactor. The reaction was described with double-substrate Michaelis- Menten kinetics. Kinetic parameters, evaluated in a 50 mL batch reactor, were used for the modelling of a microreactor, based on diffusion, convection and a non-linear reaction term, considering the velocity profile for laminar flow in a microchannel at steady-state conditions. Experimental data on L-DOPA conversions for both systems revealed good agreement with models predictions. Up to 87 % conversions of L-DOPA were achieved in a microreactor at residence times below 2 minutes.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija

POVEZANOST RADA