Naslov
Prediction of the chromatographic signal in gradient elution ion chromatography

Autori
Bolanča, Tomislav ; Cerjan Stefanović, Štefica ; Ukić, Šime ; Rogošić, Marko ; Luša, Melita

Izvornik
Journal of separation science (1615-9306) 32 (2009), 17; 2877-2884

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
ion chromatography ; retention modeling ; peak shape modeling

Sažetak
This study describes the development of a signal prediction model in gradient elution ion chromatography. The proposed model is based on a retention model and generalized logistic peak shape function which guarantees simplicity of the model and its easy implementation in method development process. Extensive analysis of the model predictive ability has been performed for ion chromatographic determination of bromate, nitrite, bromide, iodide, and perchlorate, using KOH solutions as eluent. The developed model shows good predictive ability (average relative error of gradient predictions 1.94 %). The developed model offers short calculation times (within 2.37 seconds) as well as low experimental effort (only nine isocratic runs are used for modeling).

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Kemijsko inženjerstvo

POVEZANOST RADA