Naslov
Glycosylation of glycoprotein GP62 in the stress response

Autori
Dumić, Jerka ; Lauc, Gordan ; Flögel, Mirna

Izvornik
Glycoconjugate Journal (0282-0080) 16 (1999), 11; 685-689

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
glycosylation; stress; GP62

Sažetak
GP62 is a member of the stress glycoprotein family that was proposed to have a chaperone-like function in the heat-shock response. Using lectin blotting we have studied glycosylation of GP62 and determined that in addition to heat-shock, even simple subculturing of cells is a sufficient stimulus to provoke induction of GP62. Interestingly, both kinetics of induction and glycosylation of GP62 induced by subculturing were different than when GP62 was induced by heat-shock. While GP62 induced by heat-shock was recognized by SNA, DSA and PHA-E lectins, and not by BSA I, Con A, RCA I, SJA, UEA I, VVA, and WGA lectins, GP62 induced by subculturing was also recognized by RCA I and WGA lectins.

Izvorni jezik
Engleski

Znanstvena područja
Biologija

POVEZANOST RADA